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Modulation of inflammatory signaling pathways by phytochemicals in ovarian cancer

Cited 28 time in Web of Science Cited 31 time in Scopus
Authors
Kim, Mi-Kyung; Kim, Kidong; Han, Jae Yong; Lim, Jeong Mook; Song, Yong Sang
Issue Date
2011
Publisher
Springer
Citation
Genes and Nutrition, vol.6 no.2, pp. 109-115
Keywords
PhytochemicalsOvarian cancerAnti-inflammationChemoprevention
Abstract
Inflammation has been suggested to be involved in cancer development and progression. Many clinical and experimental studies have shown that inflammation could contribute to ovarian carcinogenesis through activation of the NF-jB and AP-1 pathways by chronic inflammatory mediators. Phytochemicals, which are natural compounds derived from fruits and vegetables, have shown anti-inflammatory and anti-cancer effects. Due to their relatively low toxicity and easy accessibility, phytochemicals have been investigated for their chemopreventive potential against various cancers. In this review, we discuss the role of phytochemicals in preventing ovarian cancer through anti-inflammatory mechanisms.
ISSN
1555-8932
Language
English
URI
http://hdl.handle.net/10371/100303
DOI
https://doi.org/10.1007/s12263-011-0209-y
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College of Agriculture and Life Sciences (농업생명과학대학)Dept. of Food and Animal Biotechnology (식품·동물생명공학부)Journal Papers (저널논문_식품·동물생명공학부)
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