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Genetic modification of chicken germ cells

Cited 6 time in Web of Science Cited 8 time in Scopus
Authors
Park, Tae Sub; Han, Jae Yong
Issue Date
2012
Publisher
Wiley
Citation
Annals of the New York Academy of Sciences, vol.1271, pp. 104-109
Keywords
primordial germ cellgermline chimeratransgenesisavian biotechnology
Abstract
Over the past two decades numerous reports have demonstrated that the genetic modification of poultry genomes has great potential for improving poultry production; moreover, it may be used as a powerful tool for the production of industrial proteins. To date, transgenic techniques have been established for generating transgenic birds that express recombinant human proteins in hen eggs, as well as tissue-specific genes as an animal model. The production of transgenic birds is a promising approach that could have practical applications in agriculture and biopharmacology, in addition to advancing our understanding of avian biology. Finally, germ cell–mediated transgenesis could provide a more efficient strategy for creating gene-targeted insertions and deletions in avian species.
ISSN
0077-8923
Language
English
URI
http://hdl.handle.net/10371/100341
DOI
https://doi.org/10.1111/j.1749-6632.2012.06744.x
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College of Agriculture and Life Sciences (농업생명과학대학)Dept. of Food and Animal Biotechnology (식품·동물생명공학부)Journal Papers (저널논문_식품·동물생명공학부)
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