Publications

Detailed Information

Clinical implication of atypical cells from sputum in patients without lung cancer

Cited 1 time in Web of Science Cited 1 time in Scopus
Authors

Ko, Dong Seok; Moon, Kyung Chul; Chung, Doo Hyun; Hwang, Yong Il; Yoo, Chul-Gyu; Kim, Young Whan; Han, Sung Koo; Shim, Young-Soo; Yim, Jae-Joon

Issue Date
2006-06-15
Publisher
Blackwell Science
Citation
Respirology 2006; 11(4): 462-6.
Keywords
AgedFemaleHumansLung Neoplasms/diagnosisMaleMiddle AgedRetrospective StudiesSputum/*cytologyTime Factors
Abstract
OBJECTIVE AND BACKGROUND: Atypical-but not definitely malignant-cells in cytological examinations of sputum are usually associated with lung cancers. However, atypical cells are occasionally identified in patients without lung cancer. The aim of this study was to determine the clinical implication of the atypical cells from sputum in patients without lung cancer or other malignancies. METHODOLOGY: All patients with atypical cells observed following cytological examination of sputum on one or more occasion over a 2-year period in Seoul National University Hospital were enrolled. After exclusion of patients followed up for less than 6 months, their clinical data were reviewed retrospectively. RESULTS: Among 601 enrolled patients with atypical cells, lung cancers were diagnosed within 30 days of identification of atypical cells in 542 (90.2%) patients. Five out of 59 patients who had no evidence of lung cancer, were subsequently diagnosed with lung cancer or other malignancies following a mean observation of 164 days. In the other 54 patients without subsequent malignancies, the most common respiratory diseases were pneumonia including tuberculosis. CONCLUSIONS: The subsequent development of malignancy in patients with atypical cells in sputum despite a thorough evaluation was rare, and close observation without invasive diagnostic procedures might be simply required in these patients.
ISSN
1323-7799
Language
English
URI
https://hdl.handle.net/10371/10037
DOI
https://doi.org/10.1111/j.1440-1843.2006.00868.x
Files in This Item:
There are no files associated with this item.
Appears in Collections:

Altmetrics

Item View & Download Count

  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Share