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Alcohol consumption, body mass index and breast cancer risk by hormone receptor status: Women’ Lifestyle and Health Study

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dc.contributor.authorShin, Aesun-
dc.contributor.authorSandin, Sven-
dc.contributor.authorLof, Marie-
dc.contributor.authorMargolis, Karen L.-
dc.contributor.authorKim, Kyeezu-
dc.contributor.authorCouto, Elisabeth-
dc.contributor.authorAdami, Hans Olov-
dc.contributor.authorWeiderpass, Elisabete-
dc.date.accessioned2017-02-08T02:00:31Z-
dc.date.available2017-02-08T02:00:31Z-
dc.date.issued2015-11-09-
dc.identifier.citationBMC Cancer, 15(1):881ko_KR
dc.identifier.urihttp://hdl.handle.net/10371/100527-
dc.descriptionThis article is distributed under the terms of the Creative Commons Attribution 4.0
International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and
reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to
the Creative Commons license, and indicate if changes were made.
ko_KR
dc.description.abstractAbstract

Background
We aimed to estimate the effect of alcohol consumption on breast cancer risk and to test whether overweight and obesity modifies this association.


Methods
We included in the analysis 45,233 women enrolled in the Swedish Women’s Lifestyle and Health study between 1991 and 1992. Participants were followed for occurrence of breast cancer and death until December 2009. Poisson regression models were used, and analyses were done for overall breast cancer and for estrogen receptor positive or negative (ER+, ER-) and progesterone receptor positive and negative (PR+, PR-) tumors separately.


Results
A total of 1,385 breast cancer cases were ascertained during the follow-up period. Overall, we found no statistically significant association between alcohol intake and breast cancer risk after adjustment for confounding, with an estimated relative risk (RR) of 1.01 (95 % CI: 0.98–1.04) for an increment in alcohol consumption of 5 g/day. A statistically significant elevated breast cancer risk associated with higher alcohol consumption was found only among women with BMI ≤25 (RR 1.03, 95 % CI 1.0–1.05 per 5 g/day increase).


Conclusion
An increase in breast cancer risk with higher alcohol consumption was found for breast cancers in women with a BMI ≤25 kg/m2.
ko_KR
dc.language.isoenko_KR
dc.publisherBioMed Centralko_KR
dc.subjectBreast cancerko_KR
dc.subjectAlcoholko_KR
dc.subjectBody mass indexko_KR
dc.subjectHormone receptorko_KR
dc.titleAlcohol consumption, body mass index and breast cancer risk by hormone receptor status: Women’ Lifestyle and Health Studyko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor신애선-
dc.identifier.doi10.1186/s12885-015-1896-3-
dc.language.rfc3066en-
dc.rights.holderShin et al.-
dc.date.updated2017-01-06T10:12:44Z-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Preventive Medicine (예방의학전공)Journal Papers (저널논문_예방의학전공)
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