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Pretransplant malnutrition, inflammation, and atherosclerosis affect cardiovascular outcomes after kidney transplantation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hwang, Jin Ho | - |
dc.contributor.author | Ryu, Jiwon | - |
dc.contributor.author | An, Jung Nam | - |
dc.contributor.author | Kim, Clara Tammy | - |
dc.contributor.author | Kim, Hyosang | - |
dc.contributor.author | Yang, Jaeseok | - |
dc.contributor.author | Ha, Jongwon | - |
dc.contributor.author | Chae, Dong Wan | - |
dc.contributor.author | Ahn, Curie | - |
dc.contributor.author | Jung, In Mok | - |
dc.contributor.author | Oh, Yun Kyu | - |
dc.contributor.author | Lim, Chun Soo | - |
dc.contributor.author | Han, Duck-Jong | - |
dc.contributor.author | Park, Su-Kil | - |
dc.contributor.author | Kim, Yon Su | - |
dc.contributor.author | Kim, Young Hoon | - |
dc.contributor.author | Lee, Jung Pyo | - |
dc.date.accessioned | 2017-02-09T00:58:25Z | - |
dc.date.available | 2017-02-09T00:58:25Z | - |
dc.date.issued | 2015-07-21 | - |
dc.identifier.citation | BMC Nephrology, 16(1):109 | ko_KR |
dc.identifier.uri | https://hdl.handle.net/10371/100568 | - |
dc.description | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. | ko_KR |
dc.description.abstract | Background
Malnutrition, inflammation, and atherosclerosis (MIA) syndrome is associated with a high mortality rate in patients with end-stage renal disease. However, the clinical relevance of MIA syndrome in kidney transplantation (KT) recipients remains unknown. Methods We enrolled 1348 adult KT recipients. Recipients were assessed based on serum albumin, cholesterol, or body mass index for the malnutrition factor and C-reactive protein level for the inflammation factor. Any history of cardiovascular (CV), cerebrovascular, or peripheral vascular disease satisfied the atherosclerosis factor. Each MIA factors were assessed by univariate analysis and we calculated an overall risk score by summing up scores for each independent variable. The enrolled patients were divided into 4 groups depending on the MIA score (0, 2–4, 6, 8–10). Results The patients with higher MIA score showed worse outcome of fatal/non-fatal acute coronary syndrome (ACS) (p < 0.001) and composite outcomes of ACS and all-cause mortality (p < 0.001) than with the lower MIA score. In multivariate analysis, ACS showed significantly higher incidence in the MIA score 8-10 group than in the MIA score 0 group (Hazard ratio 6.12 95% Confidence interval 1.84–20.32 p = 0.003). Conclusions The presence of MIA factors before KT is an independent predictor of post-transplant CV outcomes. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BioMed Central | ko_KR |
dc.subject | Acute Coronary Syndrome | ko_KR |
dc.subject | Atherosclerosis | ko_KR |
dc.subject | Cardiovascular Outcome | ko_KR |
dc.subject | Inflammation | ko_KR |
dc.subject | Kidney Transplantation | ko_KR |
dc.subject | Malnutrition | ko_KR |
dc.title | Pretransplant malnutrition, inflammation, and atherosclerosis affect cardiovascular outcomes after kidney transplantation | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 황진호 | - |
dc.contributor.AlternativeAuthor | 류지원 | - |
dc.contributor.AlternativeAuthor | 안정남 | - |
dc.contributor.AlternativeAuthor | 김효상 | - |
dc.contributor.AlternativeAuthor | 양재석 | - |
dc.contributor.AlternativeAuthor | 하종원 | - |
dc.contributor.AlternativeAuthor | 채동완 | - |
dc.contributor.AlternativeAuthor | 안규리 | - |
dc.contributor.AlternativeAuthor | 정인목 | - |
dc.contributor.AlternativeAuthor | 오윤규 | - |
dc.contributor.AlternativeAuthor | 임천수 | - |
dc.contributor.AlternativeAuthor | 한덕종 | - |
dc.contributor.AlternativeAuthor | 박수길 | - |
dc.contributor.AlternativeAuthor | 김연수 | - |
dc.contributor.AlternativeAuthor | 김영훈 | - |
dc.contributor.AlternativeAuthor | 이정표 | - |
dc.identifier.doi | 10.1186/s12882-015-0108-3 | - |
dc.language.rfc3066 | en | - |
dc.rights.holder | Hwang et al. | - |
dc.date.updated | 2017-01-06T10:18:30Z | - |
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