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An international survey of physicians regarding clinical trials: a comparison between Kyoto University Hospital and Seoul National University Hospital

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Authors
Ito-Ihara, Toshiko; Hong, Jeong-Hwa; Kim, Ock-Joo; Sumi, Eriko; Kim, Soo-Youn; Tanaka, Shiro; Narita, Keiichi; Hatta, Taichi; Choi, Eun-Kyung; Choi, Kyu-Jin; Miyagawa, Takuya; Minami, Manabu; Murayama, Toshinori; Yokode, Masayuki
Issue Date
2013-10-25
Publisher
BioMed Central
Citation
BMC Medical Research Methodology, 13(1):130
Keywords
Attitude of physiciansClinical trialsQuestionnaireJapanSouth Korea
Description
This is an open access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is properly cited.
Abstract
Abstract

Background
International clinical trials are now rapidly expanding into Asia. However, the proportion of global trials is higher in South Korea compared to Japan despite implementation of similar governmental support in both countries. The difference in clinical trial environment might influence the respective physicians’ attitudes and experience towards clinical trials. Therefore, we designed a questionnaire to explore how physicians conceive the issues surrounding clinical trials in both countries.


Methods
A questionnaire survey was conducted at Kyoto University Hospital (KUHP) and Seoul National University Hospital (SNUH) in 2008. The questionnaire consisted of 15 questions and 2 open-ended questions on broad key issues relating to clinical trials.


Results
The number of responders was 301 at KUHP and 398 at SNUH. Doctors with trial experience were 196 at KUHP and 150 at SNUH. Among them, 12% (24/196) at KUHP and 41% (61/150) at SUNH had global trial experience. Most respondents at both institutions viewed clinical trials favorably and thought that conducting clinical trials contributed to medical advances, which would ultimately lead to new and better treatments. The main reason raised as a hindrance to conducting clinical trials was the lack of personnel support and time. Doctors at both university hospitals thought that more clinical research coordinators were required to conduct clinical trials more efficiently. KUHP doctors were driven mainly by pure academic interest or for their desire to find new treatments, while obtaining credits for board certification and co-authorship on manuscripts also served as motivation factors for doctors at SNUH.


Conclusions
Our results revealed that there might be two different approaches to increase clinical trial activity. One is a social level approach to establish clinical trial infrastructure providing sufficient clinical research professionals. The other is an individual level approach that would provide incentives to encourage doctors to participate in and conduct clinical trials.
Language
English
URI
http://hdl.handle.net/10371/100574
DOI
https://doi.org/10.1186/1471-2288-13-130
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of History of Medicine & Medical Humanities (의사학교실)Journal Papers (저널논문_의사학교실)
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