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Matrix metalloproteinase-1 expression inhibitory compound from the whole plants of Viola ibukiana Makino

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Authors
Moon, Hyung-In; Kim, Mi-Ran; Cho, Moon Kyun; Park, Soojie; Chung, Jin-Ho
Issue Date
2005
Publisher
John Wiley & Sons
Citation
Phytother Res 19: 239-242
Keywords
Viola ibukiana MakinoViolaceaetriterpenoid saponinsmatrix metalloproteinase-1 inhibitor
Abstract
Bioassay-guided fractionation has led to the isolation of two triterpenoid saponins 3-O-[O-beta-D-glucopyranosyl-(1 --> 3)-O-beta-D-glucopyranosyl] oleanolic acid (1), and 3-O-[O-beta-D-glucopyranosyl-(1 --> 2)-O-beta-D-glucopyranosyl] oleanolic acid (2) from the whole plants of Viola ibukiana Makino. Compound 2 showed matrix metalloproteinase-1 expression inhibition activities in a dose-dependent manner.
ISSN
0951-418X (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15934020

http://hdl.handle.net/10371/10897
DOI
https://doi.org/10.1002/ptr.1682
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College of Medicine/School of Medicine (의과대학/대학원)Dermatology (피부과학전공)Journal Papers (저널논문_피부과학전공)
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