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Reduced orbitofrontal cortical thickness in male adolescents with internet addiction

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Authors
Hong, Soon-Beom; Kim, Jae-Won; Choi, Eun-Jung; Kim, Ho-Hyun; Suh, Jeong-Eun; Kim, Chang-Dai; Klauser, Paul; Whittle, Sarah; Yűcel, Murat; Pantelis, Christos; Yi, Soon-Hyung
Issue Date
2013-03-12
Publisher
BioMed Central
Citation
Behavioral and Brain Functions, 9(1):11
Keywords
Internet addictionMagnetic resonance imagingCortical thicknessOrbitofrontal cortex
Abstract
Background
The orbitofrontal cortex (OFC) has consistently been implicated in the pathology of both drug and behavioral addictions. However, no study to date has examined OFC thickness in internet addiction. In the current study, we investigated the existence of differences in cortical thickness of the OFC in adolescents with internet addiction. On the basis of recently proposed theoretical models of addiction, we predicted a reduction of thickness in the OFC of internet addicted individuals.

Findings
Participants were 15 male adolescents diagnosed as having internet addiction and 15 male healthy comparison subjects. Brain magnetic resonance images were acquired on a 3T MRI and group differences in cortical thickness were analyzed using FreeSurfer. Our results confirmed that male adolescents with internet addiction have significantly decreased cortical thickness in the right lateral OFC (p<0.05).

Conclusion
This finding supports the view that the OFC alterations in adolescents with internet addiction reflect a shared neurobiological marker of addiction-related disorders in general.
Language
English
URI
http://hdl.handle.net/10371/109807
DOI
https://doi.org/10.1186/1744-9081-9-11
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College of Human Ecology (생활과학대학)Dept. of Consumer and Child Studies (소비자아동학부)Journal Papers (저널논문_소비자아동학부)
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