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Identifying molecular subtypes related to clinicopathologic factors in pancreatic cancer
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Shinuk | - |
dc.contributor.author | Kang, Mee Joo | - |
dc.contributor.author | Lee, Seungyeoun | - |
dc.contributor.author | Bae, Soohyun | - |
dc.contributor.author | Han, Sangjo | - |
dc.contributor.author | Jang, Jin-Young | - |
dc.contributor.author | Park, Taesung | - |
dc.date.accessioned | 2017-03-20T05:33:29Z | - |
dc.date.available | 2017-03-20T15:16:13Z | - |
dc.date.issued | 2014-12-11 | - |
dc.identifier.citation | BioMedical Engineering OnLine, 13(Suppl 2):S5 | ko_KR |
dc.identifier.uri | https://hdl.handle.net/10371/109856 | - |
dc.description.abstract | Background
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal tumors and usually presented with locally advanced and distant metastasis disease, which prevent curative resection or treatments. In this regard, we considered identifying molecular subtypes associated with clinicopathological factor as prognosis factors to stratify PDAC for appropriate treatment of patients. Results In this study, we identified three molecular subtypes which were significant on survival time and metastasis. We also identified significant genes and enriched pathways represented for each molecular subtype. Considering R0 resection patients included in each subtype, metastasis and survival times are significantly associated with subtype 1 and subtype 2. Conclusions We observed three PDAC molecular subtypes and demonstrated that those subtypes were significantly related with metastasis and survival time. The study may have utility in stratifying patients for cancer treatment. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BioMed Central | ko_KR |
dc.title | Identifying molecular subtypes related to clinicopathologic factors in pancreatic cancer | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 김신욱 | - |
dc.contributor.AlternativeAuthor | 강미주 | - |
dc.contributor.AlternativeAuthor | 이승연 | - |
dc.contributor.AlternativeAuthor | 배수현 | - |
dc.contributor.AlternativeAuthor | 한상조 | - |
dc.contributor.AlternativeAuthor | 장진영 | - |
dc.contributor.AlternativeAuthor | 박태성 | - |
dc.language.rfc3066 | en | - |
dc.rights.holder | Kim et al.; licensee BioMed Central Ltd. | - |
dc.date.updated | 2017-01-06T10:41:18Z | - |
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