CT colonography in a Korean population with a high residue diet: comparison between wet and dry preparations

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Kim, S. H.; Choi, B. I.; Han, J. K.; Lee, J. M.; Eun, H. W.; Lee, J. Y.; Lee, K. H.; Han, C. J.; Choi, Y. H.; Shin, K. S.
Issue Date
Clin Radiol 2006;61:483-94
Adenomatous Polyposis Coli/ethnology/*radiographyAsian Continental Ancestry GroupCathartics/diagnostic useColonography, Computed Tomographic/*methods/standardsEnema/methodsPolyethylene Glycols/therapeutic useSensitivity and SpecificitySolvents/therapeutic use
AIM: To compare wet and dry preparation methods for computed tomography colonography (CTC) in terms of preparation quality, interpretation time, and diagnostic performance for polyp detection in a population with a high residue diet. MATERIALS AND METHODS: Eighty-six patients were divided into two groups. Group 1 (n=24) received a wet preparation of 4l polyethylene glycol (PEG) solution, and group 2 (n=62) received a dry preparation of phosphor-soda. Abnormal findings, including polyps, and the time required to interpret the CTC images in both groups were documented by a radiologist. CTC findings were compared to those of colonoscopy as a reference standard. Two radiologists evaluated the quality of CTC with regard to residual fluid, faeces, and colonic distension using a four-point scale in consensus. Statistical differences for residual fluid, faeces, distensibility on CTC, and interpretation time between the two groups were analysed. The diagnostic performance of CTC in both groups was also compared. RESULTS: One-hundred and ninety polyps in 70 patients were identified using colonoscopy. Regarding the quality of images produced the wet preparation was significantly better than the dry preparation (p<0.05). The average interpretation time was significantly shorter for the wet group (11.7 min) than the dry group (16.4 min) (p<0.05). For per-patient analysis, the positive predictive value (PPV) was significantly better for the wet (100%) than the dry group (79.6%; p=0.025). Sensitivities and PPV for >or=10 mm polyps were comparable between two groups (p>0.05). CONCLUSION: In a population with a high-residue diet, CTC with wet preparation can be interpreted in a time-efficient manner and is comparable with CTC with dry preparation.
0009-9260 (Print)
1365-229X (Electronic)
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College of Medicine/School of Medicine (의과대학/대학원)Radiology (영상의학전공)Journal Papers (저널논문_영상의학전공)
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