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Relative and absolute risks of cigarette smoking on major histologic types of lung cancer in Korean men

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dc.contributor.authorYun, Young Ho-
dc.contributor.authorLim, Min Kyung-
dc.contributor.authorJung, Kyu Won-
dc.contributor.authorBae, Jong-Myon-
dc.contributor.authorPark, Sang Min-
dc.contributor.authorShin, Soon Ae-
dc.contributor.authorLee, Jin Soo-
dc.contributor.authorPark, Jae-Gahb-
dc.date.accessioned2009-11-09T06:22:12Z-
dc.date.available2009-11-09T06:22:12Z-
dc.date.issued2005-09-21-
dc.identifier.citationCancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2125-30en
dc.identifier.issn1055-9965 (Print)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16172220-
dc.identifier.urihttps://hdl.handle.net/10371/11586-
dc.description.abstractOBJECTIVES: Most prospective cohort studies of lung cancer focus on the relative risk rather than the absolute risk of smoking. METHODS: This prospective study included 437,976 Korean men (cohort for the National Health Insurance Cooperation Study), > or = 40 years old, who were free of cancer and smoking-related chronic disease at the time of enrollment. Based on new incidence cases, relative risk and excess risk, and their 95% confidence intervals (95% CI), were estimated with the standard Poisson regression model after adjustment for age or other demographic factors and other confounders. RESULTS: During the 6-year follow-up period of 3,142,451 person-years, 1,357 new lung cancer cases were identified. Based on the multivariate-adjusted relative risk for current smokers, the strongest association with smoking was shown for small-cell lung cancer (relative risk, 21.7; 95% CI, 8.0-58.5) followed by squamous cell carcinoma (relative risk, 11.7; 95% CI, 7.1-19.4) and then adenocarcinoma (relative risk, 2.1; 95% CI, 1.6-2.7). In current smokers with > or = 40 pack-years of exposure, excess risk was highest for squamous cell carcinoma (excess risk, 33.8; 95% CI, 10.2-109.8) followed by adenocarcinoma (excess risk, 26.7; 95% CI, 10.3-64.4), and then small-cell carcinoma (excess risk, 16.3; 95% CI, 1.8-144.3). CONCLUSIONS: In Korean men, cigarette smoking was as important a risk factor for adenocarcinoma as it was for squamous cell and small-cell lung cancer.en
dc.language.isoen-
dc.publisherAmerican Association for Cancer Researchen
dc.subjectAdenocarcinoma/ethnology/*etiology/pathologyen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectCarcinoma, Non-Small-Cell Lung/ethnology/*etiology/pathologyen
dc.subjectCarcinoma, Small Cell/ethnology/*etiology/pathologyen
dc.subjectCase-Control Studiesen
dc.subjectHumansen
dc.subjectKorea/epidemiologyen
dc.subjectLung Neoplasms/ethnology/*etiology/pathologyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectProspective Studiesen
dc.subjectRisk Factorsen
dc.subjectSmoking/*adverse effectsen
dc.titleRelative and absolute risks of cigarette smoking on major histologic types of lung cancer in Korean menen
dc.typeArticleen
dc.contributor.AlternativeAuthor윤영호-
dc.contributor.AlternativeAuthor임민경-
dc.contributor.AlternativeAuthor정규원-
dc.contributor.AlternativeAuthor배종면-
dc.contributor.AlternativeAuthor박상민-
dc.contributor.AlternativeAuthor신순애-
dc.contributor.AlternativeAuthor이진수-
dc.contributor.AlternativeAuthor박재갑-
dc.identifier.doi10.1158/1055-9965.EPI-05-0236-
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