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Superior outcomes of kidney transplantation compared with dialysis An optimal matched analysis of a national population-based cohort study between 2005 and 2008 in Korea

Cited 7 time in Web of Science Cited 8 time in Scopus
Authors
Yoo, Kyung Don; Kim, Clara Tammy; Kim, Myoung-Hee; Noh, Junhyug; Kim, Gunhee; Kim, Ho; An, Jung Nam; Park, Jae Yoon; Cho, Hyunjeong; Kim, Kyoung Hoon; Kim, Hyunwook; Ryu, Dong-Ryeol; Kim, Dong Ki; Lim, Chun Soo; Kim, Yon Su; Lee, Jung Pyo
Issue Date
2016-08
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Citation
MEDICINE Vol.95 No.33, pp. e4352
Keywords
dialysiskidney transplantationmortality
Abstract
Data regarding kidney transplantation (KT) and dialysis outcomes are rare in Asian populations. In the present study, we evaluated the clinical outcomes associated with KT using claims data from the Korean national public health insurance program. Among the 35,418 adult patients with incident dialysis treated between 2005 and 2008 in Korea, 1539 underwent KT. An optimal balanced risk set matching was attempted to compare the transplant group with the control group in terms of the overall survival and major adverse cardiac event-free survival. Before matching, the dialysis group was older and had more comorbidities. After matching, there were no differences in age, sex, dialysis modalities, or comorbidities. Patient survival was significantly better in the transplant group than in the matched control group (P<0.001). In addition, the transplant group showed better major adverse cardiac event-free survival than the dialysis group (P<0.001; hazard ratio, 0.49; 95% confidence interval, 0.32-0.75). Korean patients with incident dialysis who underwent long-term dialysis had significantly more cardiovascular events and higher all-cause mortality rates than those who underwent KT. Thus, KT should be more actively recommended in Korean populations.
ISSN
0025-7974
Language
English
URI
http://hdl.handle.net/10371/116889
DOI
https://doi.org/10.1097/MD.0000000000004352
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Computer Science and Engineering (컴퓨터공학부)Journal Papers (저널논문_컴퓨터공학부)
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