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Preparation of Antimicrobial Poly(vinyl alcohol) Nanofibers Containing Silver Nanoparticles

Cited 221 time in Web of Science Cited 234 time in Scopus
Authors
Hong, Kyung Hwa; Park, Jong Lyoul; Sul, In Hwan; Youk, Ji Ho; Kang, Tae Jin
Issue Date
2006-07-28
Publisher
Wiley-Blackwell
Citation
J Poly Sci Part B: Poly, Phys 2006, 44, 2468
Keywords
electrospinningpoly(vinyl alcohol)silver nanoparticleswound dressing
Abstract
Polyvinyl alcohol (PVA) nanofibers containing Ag nanoparticles were prepared
by electrospinning PVA/silver nitrate (AgNO3) aqueous solutions, followed by
short heat treatment, and their antimicrobial activity was investigated for wound dressing
applications. Since PVA is a water soluble and biocompatible polymer, it is one of the
best materials for the preparation of wound dressing nanofibers. After heat treatment
at 155 8C for 3 min, the PVA/AgNO3 nanofibers became insoluble, while the Agþ ions
therein were reduced so as to produce a large number of Ag nanoparticles situated preferentially
on their surface. The residual Agþ ions were reduced by subsequent UV irradiation
for 3 h. The average diameter of the Ag nanoparticles after the heat treatment
was 5.9 nm and this value increased slightly to 6.3 nm after UV irradiation. It was
found that most of the Agþ ions were reduced by the simple heat treatment. The PVA
nanofibers containing Ag nanoparticles showed very strong antimicrobial activity.
ISSN
0887-6266
Language
English
URI
http://hdl.handle.net/10371/11831
DOI
https://doi.org/10.1002/polb.20913
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Material Science and Engineering (재료공학부) Journal Papers (저널논문_재료공학부)
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