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Bronchial hyperresponsiveness in young children with allergic rhinitis and its risk factors

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dc.contributor.authorChoi, S. H.-
dc.contributor.authorYoo, Y.-
dc.contributor.authorYu, J.-
dc.contributor.authorRhee, C.-S.-
dc.contributor.authorMin, Y.-G.-
dc.contributor.authorKoh, Y. Y.-
dc.date.accessioned2009-11-13T06:23:33Z-
dc.date.available2009-11-13T06:23:33Z-
dc.date.issued2007-
dc.identifier.citationAllergy 2007;62:1051-1056en
dc.identifier.issn0105-4538 (Print)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17686108-
dc.identifier.urihttp://hdl.handle.net/10371/12139-
dc.description.abstractBACKGROUND: Subjects with allergic rhinitis but no clinical evidence of asthma have greater bronchial hyperresponsiveness (BHR), and several factors have been implicated as its determinants. However, studies in young children are lacking. The aims of this study were to evaluate the prevalence of BHR in young children with allergic rhinitis and to investigate its risk factors. METHODS: Methacholine bronchial challenges were performed in 4- to 6-year-old nonasthmatic children with allergic rhinitis (n = 83) and in healthy nonatopic controls (n = 32), using a modified auscultation method. The end-point was defined as the appearance of wheezing and/or oxygen desaturation. Subjects were considered to have BHR when they had end-point concentrations of methacholineen
dc.language.isoenen
dc.publisherWiley-Blackwellen
dc.subjectAllergens/adverse effects/immunologyen
dc.subjectBronchial Hyperreactivity/blood/*epidemiology/immunology/physiopathologyen
dc.subjectBronchial Provocation Testsen
dc.subjectImmunoglobulin E/blooden
dc.subjectMethacholine Chloride/pharmacologyen
dc.subjectPrevalenceen
dc.subjectRespiratoryen
dc.subjectHypersensitivity/blood/*epidemiology/immunology/physiopathologyen
dc.subjectRhinitis/blood/*epidemiology/immunology/physiopathologyen
dc.subjectRisk Factorsen
dc.subjectSkin Testsen
dc.titleBronchial hyperresponsiveness in young children with allergic rhinitis and its risk factorsen
dc.typeArticleen
dc.identifier.doi10.1111/j.1398-9995.2007.01403.x-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Otorhinolaryngology (이비인후과학전공)Journal Papers (저널논문_이비인후과학전공)
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