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Clinical outcomes after percutaneous pulmonary valve implantation – Systematic review and Meta-analysis

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Authors

유지선

Advisor
조성일
Major
보건대학원 보건학과
Issue Date
2014-08
Publisher
서울대학교 대학원
Keywords
percutaneous pulmonary valve implantationtranscatheter pulmonary valve implantationsystematic reviewmeta-analysis
Description
학위논문 (석사)-- 서울대학교 보건대학원 : 보건학과, 2014. 8. 조성일.
Abstract
Percutaneous pulmonary valve implantation had been used for over ten years. This study was aimed to analyze clinical outcomes after percutaneous pulmonary valve implant by systematic review and meta-analysis of preexisting published studies. Method Literature search was performed on April 2014 via PubMed and Cochrane database using NECA guideline. Out of 599 studies 10 published articles since 2005 were eligible to be included in this study. Meta-analysis was performed using RevMan. Result Significant efficacy was shown via pooled immediate hemodynamics, MRI, regurgitation outcomes. RV systolic pressure was significantly decreased (mean difference: 20.03mmHg, 95%: 17.95, 12.11). RV diastolic pressure was decreased (mean difference: 1.69mmHg, 95%: 0.94, 2.26). RV-PA gradient was reduced (mean difference: 18.96, 95%: 15.94, 21.99). End-diastolic RV volume was significantly reduced (mean difference: 26.92, 95%: 16.06, 37.77). Conclusion This study shows clinically significant improvement in safety and efficacy percutaneous pulmonary valve implantation.
Language
English
URI
https://hdl.handle.net/10371/128301
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