Effect of brace to osteoporotic vertebral fracture: a systematic review and meta-analysis

Abstract

Study design: A systematic review and meta-analysis Objects: The objective is to investigate the effect of brace on osteoporotic vertebral fracture patients through a systematically literature review and meta-analysis. Summary of Literature Review: There are 2 systematic reviews published before, neither of them included the latest published article nor comprehensively analyzed outcomes. Materials and Methods We searched electrical database with a developed searching strategy. Published randomized control trials were included in meta-analysis. We pooled data with Revman, examined the risk of bias and evaluated the quality of evidence following the guideline and handbook of Cochrane group. Results: 10 articles were included in the systematic review and 4 of them were included in meta-analysis. Low quality evidence indicates middle term use of Spinomed is better than no use in patients with subacute or chronic osteoporotic vertebral fracture on reduction of pain, correction of kyphosis angle and improvement in quality of life. Very low quality evidence proves use of Spinomed or TLSO-rigid is no better than use of soft brace to patients with acute osteoporotic vertebral fracture. Conclusions: It might be applicable to recommend middle term use of Spinomed orthosis to patients with subacute osteoporotic vertebral fracture. This systematic review highlighted the need for high quality RCTs.