Light-Induced pH-Responsive Degradation of Fumaramic Acid Derivatives
- 자연과학대학 화학부
- Issue Date
- 서울대학교 대학원
- photoisomerization; pH-sensitivity; signal-responsiveness; tandem reaction; selectivity; photochemical reaction
- 학위논문 (석사)-- 서울대학교 대학원 : 화학부, 2015. 2. 이연.
- . Fumaramic acid derivatives can be converted into their cis-isomer maleamic acid derivatives under UV illumination, and these maleamic acid derivatives show pH-responsive degradability at acidic pH only after the preceding photoisomerization. The rate of the tandem photoisomerization-degradation of fumaramic acid derivatives can be finely controlled by changing the substituents on the double bond. Photoisomerization-based unlocking of the pH-responsive degradability of fumaramic acid derivatives has strong potential for the development of multi-signal-responsive smart materials in biomedical applications.