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Gamma knife radiosurgery for central neurocytoma: primary and secondary treatment
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Chae-Yong | - |
dc.contributor.author | Paek, Sun Ha | - |
dc.contributor.author | Jeong, Sang Soon | - |
dc.contributor.author | Chung, Hyun-Tai | - |
dc.contributor.author | Han, Jung Ho | - |
dc.contributor.author | Park, Chul-Kee | - |
dc.contributor.author | Jung, Hee-Won | - |
dc.contributor.author | Kim, Dong Gyu | - |
dc.date.accessioned | 2009-11-19T03:49:48Z | - |
dc.date.available | 2009-11-19T03:49:48Z | - |
dc.date.issued | 2007-10-11 | - |
dc.identifier.citation | Cancer. 2007 Nov 15;110(10):2276-84. | en |
dc.identifier.issn | 0008-543X (Print) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17926332 | - |
dc.identifier.uri | https://hdl.handle.net/10371/13614 | - |
dc.description.abstract | BACKGROUND: Little is known about long-term results of gamma knife (GK) stereotactic radiosurgery (SRS) as a primary or a secondary postoperative therapy for central neurocytomas (CNs). The authors retrospectively reviewed long-term outcomes of 13 patients with CN treated with GK SRS. METHODS: Thirteen patients were treated with GK SRS as a primary (6 patients) or a secondary postoperative therapy (7 patients). Follow-up clinical status and brain magnetic resonance imaging (MRI) were thoroughly analyzed. The functional status of patients was assessed with the Karnofsky Performance Scale during follow-up. RESULTS: The median follow-up period for clinical status and imaging studies was 61 months (range, 6 months to 96 months). Tumors decreased in 5 patients who received GK SRS as a primary treatment. However, the tumor recurred in 2 patients treated with a secondary GK SRS after surgery from the residual tumor bed that was not covered by the GK SRS. Parenchymal changes and secondary malignancies were not found in follow-up MRIs of all 13 patients. The Karnofsky Performance Scale score of all patients, except for 1 patient who suffered from an unrelated anteriorly communicating arterial aneurysmal rupture, did not change after GK SRS. CONCLUSIONS: GK SRS may be useful as a primary or a secondary postoperative therapy for the treatment of CN. However, more attention should be paid to residual or recurrent CN during treatment, and regular long-term follow-up MRI should be mandatory to validate the procedure. | en |
dc.language.iso | en | en |
dc.publisher | John Wiley & Sons | en |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | Brain Neoplasms/*surgery | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Neurocytoma/*surgery | en |
dc.subject | Retrospective Studies | en |
dc.subject | Treatment Outcome | en |
dc.subject | Radiosurgery | - |
dc.title | Gamma knife radiosurgery for central neurocytoma: primary and secondary treatment | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 김재용 | - |
dc.contributor.AlternativeAuthor | 백선하 | - |
dc.contributor.AlternativeAuthor | 정상훈 | - |
dc.contributor.AlternativeAuthor | 정현태 | - |
dc.contributor.AlternativeAuthor | 한정호 | - |
dc.contributor.AlternativeAuthor | 박철기 | - |
dc.contributor.AlternativeAuthor | 정희원 | - |
dc.contributor.AlternativeAuthor | 김동규 | - |
dc.identifier.doi | 10.1002/cncr.23036 | - |
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