S-Space College of Medicine/School of Medicine (의과대학/대학원) Thoracic Surgery (흉부외과학전공) Journal Papers (저널논문_흉부외과학전공)
One-stage total repair of aortic arch anomaly using regional perfusion
- Lim, Hong-Gook; Kim, Woong-Han; Jang, Woo-Sung; Lim, Cheong; Kwak, Jae Gun; Lee, Cheul; Hwang, Seong Wook
- Issue Date
- Eur J Cardiothorac Surg. 2007 Feb;31(2):242-8. Epub 2006 Nov 28.
- Aortic Arch Syndromes/*surgery; Aortic Coarctation/surgery; Brain Diseases/prevention & control; Cardiopulmonary Bypass; Cerebrovascular Circulation; Follow-Up Studies; Heart Arrest, Induced/methods; Heart Septal Defects, Ventricular/surgery; Humans; Infant; Infant, Newborn; Perfusion/methods; Postoperative Complications; Treatment Outcome
- OBJECTIVE: Primary repair of aortic arch obstructions and associated cardiac anomalies is a surgical challenge in neonates and infants. Deep hypothermic circulatory arrest prolongs myocardial ischemia and might induce cerebral and myocardial dysfunction. METHODS: From March 2000 to December 2005, 69 neonates or infants with aortic arch anomaly underwent one-stage biventricular repair with continuous cerebral perfusion in the presence of a nonworking beating heart using the dual perfusion technique on the innominate artery and aortic root. Preoperative diagnoses of arch anomaly comprised aortic coarctation (n=54) or an interrupted aortic arch (n=15). Combined anomalies were ventricular septal defect (n=52), anomalous origin of the right pulmonary artery from ascending aorta (n=3), hypoplastic left heart syndrome (n=2), truncus arteriosus (n=2), atrioventricular septal defect (n=2), double outlet right ventricle (n=1), total anomalous pulmonary venous return (n=1), partial anomalous pulmonary venous return (n=1), and aortic stenosis (n=1). RESULTS: The mean regional perfusion time was 27.8+/-9.8 min. There was no operative mortality. Postoperative low cardiac output was present in four patients (5.8%). A neurologic complication was noted in one patient (1.5%) who developed transient chorea, but recovered completely. During 32.8+/-17.5 months of follow-up, one late death (1.5%) occurred. There was neither reoperation associated with arch anomaly nor recoarctation except in one patient. One patient developed left main bronchial compression necessitating aortopexy. CONCLUSIONS: One-stage total arch repair using our regional perfusion technique is an excellent method that may minimize neurologic and myocardial complications without mortality. Our surgical strategy for arch anomaly has a low rate of residual and recurrent coarctation when performed in neonates and infants.
- 1010-7940 (Print)
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