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Pathogenic genotype of major piroplasm surface protein associated with anemia in Theileria orientalis infection in cattle
Cited 10 time in
Web of Science
Cited 9 time in Scopus
- Authors
- Issue Date
- 2017-07-27
- Publisher
- BioMed Central
- Citation
- Acta Veterinaria Scandinavica, 59(1):51
- Keywords
- Anemia ; Major piroplasm surface protein ; MPSP type 1 ; Theileria orientalis
- Description
- Abbreviations
EDTA: ethylenediaminetetraacetic acid; Hb: hemoglobin; HCT: hematocrit; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; MCV: mean cell volume; MPSP: major piroplasm surface protein; PCR: polymerase chain reaction; RBC: red blood cell; rRNA: ribosomal RNA; T. orientalis: Theileria orientalis
- Abstract
- Abstract
Serious disease outbreaks in cattle caused by Theileria orientalis have emerged in the Asia–Pacific region. Genetic variables of the major piroplasm surface protein (MPSP) expressed on the surface of the piroplasm inside T. orientalis-infected erythrocytes are considered to be associated with variation in the pathogenicity of T. orientalis. Our study describes the clinically relevant MPSP types associated with anemia in Theileria-infected cattle. These results revealed that MPSP expression plays an important role in hematological alterations in Theileria-infected cattle, and that MPSP type 1 is strongly associated with bovine anemia, which can be a potential target for the prevention of bovine theileriosis.
- ISSN
- 1751-0147
- Language
- English
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