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Treatment of non-odontogenic orofacial pain using botulinum toxin-A: a retrospective case series study

Cited 4 time in Web of Science Cited 0 time in Scopus
Authors
Kim, Sang-Yun; Kim, Young-Kyun; Yun, Pil-Young; Bae, Ji-Hyun
Issue Date
2018-08-06
Publisher
Springer Open
Citation
Maxillofacial Plastic and Reconstructive Surgery, 40(1):21
Keywords
Orofacial painBotulinum toxinBTX-A
Abstract
Background
The purpose of this study was to evaluate the clinical outcomes of treatment of non-odontogenic atypical orofacial pain using botulinum toxin-A.

Methods
This study involved seven patients (seven females, mean age 65.1 years) who had non-odontogenic orofacial pain (neuropathic pain and atypical orofacial pain) and visited the Seoul National University Bundang Hospital between 2015 and 2017. All medication therapies were preceded by botulinum toxin-A injections, followed by injections in the insignificant effects of medication therapies. Five of the seven patients received intraoral injections in the gingival vestibule or mucosa, while the remaining two received extraoral injections in the masseter and temporal muscle areas.

Results
In five of the seven patients, pain after botulinum toxin-A injection was significantly reduced. Most of the patients who underwent surgery for dental implantation or facial nerve reconstruction recovered after injections. However, the pain did not disappear in two patients who reported experiencing persistent pain without any cause.

Conclusions
The use of botulinum toxin-A for the treatment of non-odontogenic neuropathic orofacial pain is clinically useful. It is more effective to administer botulinum toxin-A in combination with other medications and physical therapy to improve pain.
ISSN
2288-8586
Language
English
URI
http://hdl.handle.net/10371/143535
DOI
https://doi.org/10.1186/s40902-018-0159-z
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College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
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