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Accuracy of MR imaging for the prediction of myometrial invasion of endometrial carcinoma

Cited 73 time in Web of Science Cited 81 time in Scopus
Authors
Chung, Hyun Hoon; Kang, Soon-Beom; Cho, Jeong Yeon; Kim, Jae Weon; Park, Noh-Hyun; Song, Yong-Sang; Kim, Seung Hyup; Lee, Hyo-Pyo
Issue Date
2006-11-11
Publisher
Elsevier
Citation
Gynecol Oncol. 2007 Mar;104(3):654-9. Epub 2006 Nov 13.
Keywords
AdultAgedAged, 80 and overEndometrial Neoplasms/*pathologyFalse Negative ReactionsFemaleHumansLymphatic MetastasisMagnetic Resonance ImagingMiddle AgedMyometrium/*pathologyNeoplasm InvasivenessPredictive Value of TestsRetrospective StudiesSensitivity and Specificity
Abstract
OBJECTIVES: To retrospectively evaluate the accuracy of magnetic resonance (MR) imaging for the prediction of depth of myometrial invasion in the preoperative assessment of women with endometrial carcinoma. METHODS: We retrospectively reviewed the medical records and MR imaging reports of 120 women with pathologically-proven endometrial carcinoma who underwent preoperative pelvic MR imaging between June 1997 and February 2006. Tumor signal intensity, the appearance of the junctional zone (JZ), the presence of large polypoid tumors and leiomyomas were analyzed. Univariate logistic-regression analysis was performed to identify associations between incorrect MR staging and the study variables. RESULTS: Data from 120 patients were registered for the current study and analyzed. The sensitivity, specificity and accuracy of the MR imaging in assessment of myometrial invasion among patients with endometrial carcinoma were: 50.6%, 89.2% and 62.5% respectively. MR differentiation of deep myometrial invasion from superficial disease had an 83.3% accuracy (100 of 120 cases). Isointense JZ to myometrium (P<0.001), and the presence of polypoid tumors (P=0.037) on MR imaging were significantly associated with an underestimation of myometrial invasion by endometrial carcinoma. CONCLUSIONS: Isointense JZ to myometrium and polypoid tumors are difficult to accurately evaluate for myometrial invasion of endometrial carcinoma by MR imaging.
ISSN
0090-8258 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17095081

http://hdl.handle.net/10371/15287
DOI
https://doi.org/10.1016/j.ygyno.2006.10.007
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College of Medicine/School of Medicine (의과대학/대학원)Obstetrics & Gynecology (산부인과전공)Journal Papers (저널논문_산부인과학전공)
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