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Association between dental health and obstructive coronary artery disease: an observational study

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Authors
Lee, Ho; Kim, Hack-Lyoung; Jin, Kwang Nam; Oh, Sohee; Han, Yoon-Sic; Jung, Da-Un; Sim, Hye-Young; Kim, Hee-Sun; Lim, Woo-Hyun; Seo, Jae-Bin; Kim, Sang-Hyun; Zo, Joo-Hee; Kim, Myung-A
Issue Date
2019-04-27
Citation
BMC Cardiovascular Disorders, 19(1):98
Keywords
Coronary artery diseaseDental healthInflammationTooth loss
Abstract
Background
The association between dental health and coronary artery disease (CAD) remains a topic of debate. This study aimed to investigate the association between dental health and obstructive CAD using multiple dental indices.

Methods
Eighty-eight patients (mean age: 65 years, 86% male) were prospectively enrolled before undergoing coronary CT angiography (n = 52) or invasive coronary angiography (n = 36). Obstructive CAD was defined as luminal stenosis of ≥50% for the left main coronary artery or ≥ 70% for the other epicardial coronary arteries. All patients underwent thorough dental examinations to evaluate 7 dental health indices, including the sum of decayed and filled teeth, the ratio of no restoration, the community periodontal index of treatment needs, clinical attachment loss, the total dental index, the panoramic topography index, and number of lost teeth.

Results
Forty patients (45.4%) had obstructive CAD. Among the 7 dental health indices, only the number of lost teeth was significantly associated with obstructive CAD, with patients who had obstructive CAD having significantly more lost teeth than patients without obstructive CAD (13.08 ± 10.4 vs. 5.44 ± 5.74, p < 0.001). The number of lost teeth was correlated with the number of obstructed coronary arteries (p < 0.001). Multiple binary logistic regression analysis revealed that having ≥10 lost teeth was independently associated with the presence of obstructive CAD (odds ratio: 8.02, 95% confidence interval: 1.80–35.64; p = 0.006).

Conclusions
Tooth loss was associated with the presence of obstructive CAD in patients undergoing coronary evaluation. Larger longitudinal studies are needed to determine whether there is a causal relationship between tooth loss and CAD.
ISSN
1471-2261
Language
English
URI
http://hdl.handle.net/10371/153251
DOI
https://doi.org/10.1186/s12872-019-1080-9
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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