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The use of gold nanoparticle aggregation for DNA computing and logic-based biomolecular detection

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Authors
Lee, In-Hee; Yang, Kyung-Ae; Lee, Ji-Hoon; Park, Ji-Yoon; Chai, Young Kyu; Lee, Jae-Hoon; Zhang, Byoung-Tak
Issue Date
2008-08-08
Publisher
Institute of Physics
Citation
Nanotechnology 19 395103
Keywords
nanoparticle; DNA computing; biomolecular detection; gold
Abstract
The use of DNA molecules as a physical computational material has attracted much interest, especially in the area of DNA computing. DNAs are also useful for logical control and analysis of biological systems if efficient visualization methods are available. Here we present a quick
and simple visualization technique that displays the results of the DNA computing process based on a colorimetric change induced by gold nanoparticle aggregation, and we apply it to the logic-based detection of biomolecules. Our results demonstrate its effectiveness in both DNA-based logical computation and logic-based biomolecular detection.
ISSN
0957-4484
Language
English
URI
http://hdl.handle.net/10371/1624
DOI
https://doi.org/10.1088/0957-4484/19/39/395103
https://doi.org/10.1088/0957-4484/19/39/395103
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Computer Science and Engineering (컴퓨터공학부)Journal Papers (저널논문_컴퓨터공학부)
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