Publications
Detailed Information
Evaluation of the efficacy of ivermectin against Theileria orientalis infection in grazing cattle
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Jinho | - |
dc.contributor.author | Chae, Jeong-Byoung | - |
dc.contributor.author | Kim, Suhee | - |
dc.contributor.author | Yu, Do-Hyeon | - |
dc.contributor.author | Kim, Hyeon-Cheol | - |
dc.contributor.author | Park, Bae-Keun | - |
dc.contributor.author | Chae, Joon-Seok | - |
dc.contributor.author | Choi, Kyoung-Seong | - |
dc.date.accessioned | 2019-10-31T07:27:02Z | - |
dc.date.available | 2019-10-31T16:30:40Z | - |
dc.date.issued | 2019-08-17 | - |
dc.identifier.citation | BMC Veterinary Research, 15(1):297 | ko_KR |
dc.identifier.issn | 1746-6148 | - |
dc.identifier.uri | https://hdl.handle.net/10371/162607 | - |
dc.description.abstract | Background
Raising cattle on pastures is known to be beneficial for animal welfare and cost reduction. However, grazing is associated with the risk of contracting tick-borne diseases, such as theileriosis. Here, the efficacy of ivermectin against these diseases and associated clinical symptoms were evaluated. Results A total of 68 cattle from a grazing cattle farm were selected and divided into two groups: the control group (17 cattle) with no preventive treatment and the ivermectin-treated group (51 cattle) in which cattle were treated with pour-on ivermectin prior to grazing. The infection rates of Theileria orientalis and the red blood cell (RBC) profile (e.g., RBC count, hematocrit value, and hemoglobin concentration) were compared in the spring (before grazing) and summer (during grazing) between the two groups. Based on PCR amplification of the major piroplasm surface protein (MPSP) gene, 12 cattle were positive for T. orientalis infection. Phylogenetic analysis revealed that the isolates identified in this study consisted of three MPSP types (1, 2, and 7). The T. orientalis infection rate in the control group during grazing was 3-fold higher than that in the ivermectin-treated group. Moreover, differences in RBC parameters during grazing were greater in the control group than in the ivermectin-treated group. In particular, the hematocrit value was significantly reduced in the control group. Conclusions The results of this study demonstrated that ivermectin had protective effects against T. orientalis infection and RBC hemolysis in grazing cattle. | ko_KR |
dc.description.sponsorship | This work was supported by the Ministry of Education of the Republic of Korea and the National Research Foundation of Korea (NRF2017R1A2B2005685). This research was partially supported by Technology Development Program (Project No. 1116043–1) for Bio-industry, Ministry for Agriculture, Food and Rural Affairs, Republic of Korea. The funders had no role in the study design, data collection and analysis, interpretation of results, writing of the report, decision to submit the paper for publication. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BioMed Central | ko_KR |
dc.subject | Grazing | ko_KR |
dc.subject | Hematocrit | ko_KR |
dc.subject | Ivermectin | ko_KR |
dc.subject | Theileria orientalis | ko_KR |
dc.title | Evaluation of the efficacy of ivermectin against Theileria orientalis infection in grazing cattle | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 박진호 | - |
dc.contributor.AlternativeAuthor | 채정병 | - |
dc.contributor.AlternativeAuthor | 김수희 | - |
dc.contributor.AlternativeAuthor | 유도현 | - |
dc.contributor.AlternativeAuthor | 김현철 | - |
dc.contributor.AlternativeAuthor | 박배근 | - |
dc.contributor.AlternativeAuthor | 채준석 | - |
dc.contributor.AlternativeAuthor | 최경성 | - |
dc.identifier.doi | 10.1186/s12917-019-2042-2 | - |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s). | - |
dc.date.updated | 2019-08-18T03:28:25Z | - |
- Appears in Collections:
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.