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Bioinspired surface immobilization of hyaluronic acid on monodisperse magnetite nanocrystals for targeted cancer imaging

Cited 295 time in Web of Science Cited 305 time in Scopus
Authors

Lee, Yuhan; Lee, Haeshin; Kim, Young Beom; Kim, Jaeyoon; Hyeon, Taeghwan; Park, HyunWook; Messersmith, Phillip B.; Park, Tae Gwan

Issue Date
2008-11
Publisher
WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Citation
Advanced Materials, Vol.20 No.21, pp.4154-4157
Abstract
Hyaluronic-acid immobilized monodisperse magnetic nanocrystals (HA-DN/MNCs) are synthesized. Dopamine, the analogue of 3,4-dihydroxy-L-phenylalanine responsible for the adhesion properties in proteins excreted by mussels, plays a key role in the surface modification of nanocrystals. HA-DN/MNCs exhibit great stability in aqueous solution, applicable for in vivo targeted-cancer imaging.
ISSN
0935-9648
URI
https://hdl.handle.net/10371/165845
DOI
https://doi.org/10.1002/adma.200800756
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  • College of Engineering
  • School of Chemical and Biological Engineering
Research Area Chemistry, Materials Science

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