Browse

Multifunctional nanoparticles as a tissue adhesive and an injectable marker for image-guided procedures

DC Field Value Language
dc.contributor.authorShin, Kwangsoo-
dc.contributor.authorChoi, Jin Woo-
dc.contributor.authorKo, Giho-
dc.contributor.authorBaik, Seungmin-
dc.contributor.authorKim, Dokyoon-
dc.contributor.authorPark, Ok Kyu-
dc.contributor.authorLee, Kyoungbun-
dc.contributor.authorCho, Hye Rim-
dc.contributor.authorHan, Sang Ihn-
dc.contributor.authorLee, Soo Hong-
dc.contributor.authorLee, Dong Jun-
dc.contributor.authorLee, Nohyun-
dc.contributor.authorKim, Hyo-Cheol-
dc.contributor.authorHyeon, Taeghwan-
dc.date.accessioned2020-04-27T13:30:01Z-
dc.date.available2020-04-27T13:30:01Z-
dc.date.issued2017-07-
dc.identifier.citationNature Communications, Vol.8, p. 15807-
dc.identifier.issn2041-1723-
dc.identifier.other49683-
dc.identifier.urihttp://hdl.handle.net/10371/165919-
dc.description.abstractTissue adhesives have emerged as an alternative to sutures and staples for wound closure and reconnection of injured tissues after surgery or trauma. Owing to their convenience and effectiveness, these adhesives have received growing attention particularly in minimally invasive procedures. For safe and accurate applications, tissue adhesives should be detectable via clinical imaging modalities and be highly biocompatible for intracorporeal procedures. However, few adhesives meet all these requirements. Herein, we show that biocompatible tantalum oxide/silica core/shell nanoparticles (TSNs) exhibit not only high contrast effects for real-time imaging but also strong adhesive properties. Furthermore, the biocompatible TSNs cause much less cellular toxicity and less inflammation than a clinically used, imageable tissue adhesive (that is, a mixture of cyanoacrylate and Lipiodol). Because of their multifunctional imaging and adhesive property, the TSNs are successfully applied as a hemostatic adhesive for minimally invasive procedures and as an immobilized marker for image-guided procedures.-
dc.titleMultifunctional nanoparticles as a tissue adhesive and an injectable marker for image-guided procedures-
dc.typeArticle-
dc.contributor.AlternativeAuthor현택환-
dc.identifier.doi10.1038/ncomms15807-
dc.citation.journaltitleNature Communications-
dc.identifier.scopusid2-s2.0-85025068656-
dc.citation.startpage15807-
dc.citation.volume8-
dc.identifier.urlhttps://www.nature.com/articles/ncomms15807-
dc.identifier.rimsid49683-
dc.identifier.sci000405815500001-
dc.description.isOpenAccessY-
dc.contributor.affiliatedAuthorHyeon, Taeghwan-
Appears in Collections:
College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Journal Papers (저널논문_화학생물공학부)
College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Chemical Convergence for Energy and Environment (에너지환경 화학융합기술전공)Journal Papers (저널논문_에너지환경 화학융합기술전공)
Files in This Item:
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse