Early versus late intravitreal triamcinolone acetonide for macular edema associated with branch retinal vein occlusion

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Oh, Joo Youn; Seo, Je Hyun; Ahn, Jae Kyoun; Heo, Jang Won; Chung, Hum
Issue Date
Korean Journal of Ophthalmology
Korean J Ophthalmol. 2007 Mar;21(1):18-20.
Drug Administration ScheduleFemaleFovea Centralis/drug effectsGlucocorticoids/*administration & dosage/therapeutic useHumansMacular Edema/chemically induced/*drug therapy/physiopathologyMaleMiddle AgedRetinal Vein Occlusion/*complicationsTomography, Optical CoherenceTreatment OutcomeTriamcinolone Acetonide/*administration & dosage/therapeutic useVisual Acuity/drug effects
PURPOSE: To compare the effect of early versus late intravitreal injection of triamcinolone in patients with macular edema due to branch retinal vein occlusion (BRVO). METHODS: Twenty eyes of 20 patients with macular edema from BRVO, including 10 with duration after onset of or <or= 3 months and 10 with duration of 3 months, were treated using a single intravitreal triamcinolone injection (4 mg/0.1 ml). Best-corrected visual acuity and foveal thickness by optical coherence tomography were measured 1, 3, and 6 months post-injection. RESULTS: In patients that received treatment after a disease duration of <or= 3 months, visual acuity and foveal thickness significantly improved from baseline over 6 months of follow-up. However, in those with a duration of >3 months, improvements in visual acuity and foveal thickness, though apparent at 1 month, were not maintained at 3 and 6 months post-triamcinolone. CONCLUSIONS: Intravitreal triamcinolone is more effective in patients with BRVO who are treated earlier.
1011-8942 (Print)
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College of Medicine/School of Medicine (의과대학/대학원)Ophthalmology (안과학전공)Journal Papers (저널논문_안과학전공)
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