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Multifunctional Fe 3O 4/TaO x core/shell nanoparticles for simultaneous magnetic resonance imaging and X-ray computed tomography
Cited 202 time in
Web of Science
Cited 213 time in Scopus
- Authors
- Issue Date
- 2012-06
- Publisher
- American Chemical Society
- Citation
- Journal of the American Chemical Society, Vol.134 No.25, pp.10309-10312
- Abstract
- Multimodal imaging is highly desirable for accurate diagnosis because it can provide complementary information from each imaging modality. In this study, a sol-gel reaction of tantalum(V) ethoxide in a microemulsion containing Fe3O4 nanoparticles (NPs) was used to synthesize multifunctional Fe3O4/TaOx core/shell NPs, which were biocompatible and exhibited a prolonged circulation time. When the NPs were intravenously injected, the tumor-associated vessel was observed using computed tomography (CT), and magnetic resonance imaging (MRI) revealed the high and low vascular regions of the tumor.
- ISSN
- 0002-7863
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