Publications
Detailed Information
Adiponectin in severe preeclampsia
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Nien, Jyh Kae | - |
dc.contributor.author | Mazaki-Tovi, Shali | - |
dc.contributor.author | Romero, Roberto | - |
dc.contributor.author | Erez, Offer | - |
dc.contributor.author | Kusanovic, Juan Pedro | - |
dc.contributor.author | Gotsch, Francesca | - |
dc.contributor.author | Pineles, Beth L | - |
dc.contributor.author | Gomez, Ricardo | - |
dc.contributor.author | Edwin, Samuel | - |
dc.contributor.author | Mazor, Moshe | - |
dc.contributor.author | Espinoza, Jimmy | - |
dc.contributor.author | Yoon, Bo Hyun | - |
dc.contributor.author | Hassan, Sonia S | - |
dc.date.accessioned | 2009-12-17T09:10:08Z | - |
dc.date.available | 2009-12-17T09:10:08Z | - |
dc.date.issued | 2007-10-09 | - |
dc.identifier.citation | J Perinat Med 2007;35:503-512 | en |
dc.identifier.issn | 0300-5577 (Print) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17919115 | - |
dc.identifier.uri | https://hdl.handle.net/10371/21301 | - |
dc.description.abstract | AIMS: Adiponectin is an adipokine with insulin-sensitizing, anti-atherogenic, anti-inflammatory and angiogenic properties. The aims of this study were to determine whether maternal plasma adiponectin concentrations differ between patients with severe preeclampsia and those with normal pregnancies, and to explore the relationship between plasma adiponectin and the results of Doppler velocimetry of the uterine arteries. METHODS: This case-control study included two groups: (1) patients with severe preeclampsia (n=50) and (2) patients with normal pregnancies (n=150). Pulsed-wave and color Doppler ultrasound examination of the uterine arteries were performed. Plasma adiponectin concentrations were determined by ELISA. Non-parametric statistics were used for analysis. RESULTS: (1) Patients with severe preeclampsia had a higher median plasma concentration of adiponectin than that of normal pregnant women. (2) The median plasma adiponectin concentration did not differ between women with severe preeclampsia who had a high impedance to blood flow in the uterine arteries and those with normal impedance to blood flow. (3) Among patients with normal pregnancies, plasma adiponectin concentrations were negatively correlated with BMI in the first trimester and at sampling. CONCLUSIONS: Women with severe preeclampsia have a higher median plasma concentration of adiponectin than that of normal pregnant women. This may reflect a compensatory feedback mechanism to the metabolically-altered, anti-angiogenic and pro-atherogenic state of severe preeclampsia. | en |
dc.language.iso | en | - |
dc.publisher | Walter de Gruyter | en |
dc.subject | Adiponectin/*blood | en |
dc.subject | Case-Control Studies | en |
dc.subject | Pre-Eclampsia/*blood | en |
dc.subject | Pregnancy | en |
dc.subject | Severity of Illness Index | en |
dc.subject | Ultrasonography, Doppler | en |
dc.subject | Uterus/*blood supply/*ultrasonography | en |
dc.title | Adiponectin in severe preeclampsia | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 윤보현 | - |
dc.identifier.doi | 10.1515/JPM.2007.121 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.