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Renal tissue reconstitution by the implantation of renal segments on biodegradable polymer scaffolds

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Authors
Kim, S. S.; Park, H. J.; Han, J.; Choi, C. Y.; Kim, B. S.
Issue Date
2003-10-24
Publisher
Springer Verlag
Citation
Biotechnol Lett. 2003 Sep;25(18):1505-8.
Keywords
*Absorbable ImplantsAnimalsAnimals, NewbornCell Division/physiologyCulture Techniques/*methodsExtracellular Matrix/physiologyGraft Survival/*physiologyKidney/*cytology/*growth & development/surgeryKidney Transplantation/*methodsMembranes, ArtificialPolyglycolic AcidRatsRats, Sprague-DawleyRegeneration/*physiologyTissue Engineering/*methods
Abstract
Renal units were created in vivo by transplanting isolated renal segments on three-dimensional, biodegradable polymer scaffolds. Renal segments, freshly isolated from rat kidneys, were seeded on polymer scaffolds and subcutaneously implanted in athymic mice for two and four weeks. Three-dimensional renal reconstructs were formed with glomeruli and tubules, showing a possibility of reconstituting renal structures by transplanting renal segments.
ISSN
0141-5492 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14571973

http://hdl.handle.net/10371/22347
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College of Medicine/School of Medicine (의과대학/대학원)Neuroscience (뇌신경과학전공)Journal Papers (저널논문_뇌신경과학전공)
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