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Reduced immunoreactivities of a vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptor (VPAC1 receptor) in the cerebral cortex, hippocampal region, and amygdala of aged rats

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dc.contributor.authorJoo, Kyeung Min-
dc.contributor.authorChung, Yoon Hee-
dc.contributor.authorLim, Heon-chang-
dc.contributor.authorLee, Kyung Hoon-
dc.contributor.authorCha, Choong Ik-
dc.date.accessioned2009-12-28T02:37:09Z-
dc.date.available2009-12-28T02:37:09Z-
dc.date.issued2005-11-05-
dc.identifier.citationBrain Res. 2005 Dec 7;1064(1-2):166-72. Epub 2005 Nov 2.en
dc.identifier.issn0006-8993 (Print)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16269138-
dc.identifier.urihttp://hdl.handle.net/10371/22839-
dc.description.abstractIn this study, we examined expressional changes of VPAC1 receptor in aged rat brains using an immunohistochemical approach and found that its immunoreactivities are significantly reduced in the cerebral cortex, hippocampal region, and amygdala of aged rats. These results suggest that this reduction could underlie aging-associated memory/learning deficits and several other age-induced functional changes in these areas. However, the functional consequences of these down-regulations require further elucidation.en
dc.language.isoen-
dc.publisherElsevieren
dc.subjectAging/*metabolismen
dc.subjectAmygdala/metabolismen
dc.subjectAnimalsen
dc.subjectBrain/*metabolismen
dc.subjectCerebral Cortex/metabolismen
dc.subjectHippocampus/metabolismen
dc.subjectImmunohistochemistryen
dc.subjectMaleen
dc.subjectRatsen
dc.subjectReceptors, Vasoactive Intestinal Polypeptide, Type I/*metabolismen
dc.subjectTissue Distributionen
dc.subjectVasoactive Intestinal Peptide/*metabolismen
dc.titleReduced immunoreactivities of a vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptor (VPAC1 receptor) in the cerebral cortex, hippocampal region, and amygdala of aged ratsen
dc.typeArticleen
dc.contributor.AlternativeAuthor주경민-
dc.contributor.AlternativeAuthor정윤희-
dc.contributor.AlternativeAuthor임헌창-
dc.contributor.AlternativeAuthor이경훈-
dc.contributor.AlternativeAuthor차충익-
dc.identifier.doi10.1016/j.brainres.2005.09.006-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Anatomy (해부학전공)Journal Papers (저널논문_해부학전공)
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