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Clear-cell Ependymoma of the Cerebellum: A Case Report
Cited 4 time in
Web of Science
Cited 6 time in Scopus
- Authors
- Issue Date
- 2007
- Publisher
- Ultrastructural pathology
- Citation
- Ultrastructural Pathology. 2007;31:241–247
- Keywords
- cerebellum ; child ; clear cell ependymoma ; immunohistochemistry ; ultrastructure
- Abstract
- A case of clear-cell ependymoma occurring in the cerebellum of a 3-year-old girl is reported. Light-microscopically, the tumor consisted mainly of clear cells with a perinuclear halo and showed some vague perivascular pseudorosettes, not true rosettes. In addition, the histological features of anaplasia, characterized by increased mitosis and focal pseudopalisading necrosis, were also observed. Immunohistochemically, the tumor cells were focally positive for glial fibrillary acidic protein and weakly positive for epithelial membrane antigen. Ultrastructurally, the intermediate junctions and rudimentary cilia confirmed the ependymal differentiation. Fifteen cases of infratentorial clear-cell ependymoma have been reported to date, and this case is the second childhood tumor among them, to the best of the authors' knowledge.
- ISSN
- 1521-0758 (Electronic)
- Language
- English
- URI
- http://www.informaworld.com/smpp/content~db=all?content=10.1080/01913120701446841
https://hdl.handle.net/10371/23397
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