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A case of atypical hemolytic uremic syndrome with a transient decrease in complement factor H

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Authors
Hahn, Hyewon; Um, Eun Young; Park, Young Seo; Cheong, Hae Il
Issue Date
2005-12-20
Publisher
Springer Verlag
Citation
Pediatr Nephrol. 2006 Feb;21(2):295-8. Epub 2005 Dec 17.
Keywords
Child, PreschoolComplement Factor H/*analysisHemolytic-Uremic Syndrome/*blood/diagnosisHumansMale
Abstract
We report a case of sporadic atypical hemolytic uremic syndrome (HUS) with a transient decrease in complement factor H. Referred for hemolysis and azotemia without diarrhea prodrome, this 31-month-old boy showed a decreased complement 3 (C3) and complement factor H (FH) level. However, the factor H gene (HF1) mutation was missing. After the hemolysis was controlled with plasma infusion, the C3 and FH levels recovered. The patient's renal function fully recovered and remained normal, and there was no recurrence of the HUS.
ISSN
0931-041X (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16362720

http://hdl.handle.net/10371/24633
DOI
https://doi.org/10.1007/s00467-005-2108-1
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College of Medicine/School of Medicine (의과대학/대학원)Pediatrics (소아과학전공)Journal Papers (저널논문_소아과학전공)
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