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Decreased cerebral blood flow of the right anterior cingulate cortex in long-term and short-term abstinent methamphetamine users

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dc.contributor.authorHwang, Jaeuk-
dc.contributor.authorLyoo, In Kyoon-
dc.contributor.authorKim, Seog Ju-
dc.contributor.authorSung, Young Hoon-
dc.contributor.authorBae, Soojeong-
dc.contributor.authorCho, Sung-Nam-
dc.contributor.authorLee, Ho Young-
dc.contributor.authorLee, Dong Soo-
dc.contributor.authorRenshaw, Perry F-
dc.date.accessioned2009-12-31T08:02:46Z-
dc.date.available2009-12-31T08:02:46Z-
dc.date.issued2005-10-29-
dc.identifier.citationDrug Alcohol Depend. 2006 Apr 28;82(2):177-81. Epub 2005 Oct 25.en
dc.identifier.issn0376-8716 (Print)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16253441-
dc.identifier.urihttp://hdl.handle.net/10371/24681-
dc.description.abstractBACKGROUND: The aim of the current study was to explore changes of relative regional cerebral blood flow (rCBF) in short-term and long-term abstinent methamphetamine (MA) users. METHODS: Relative rCBF in 40 abstinent MA users and 23 healthy comparison subjects was compared by the technetium-99m-hexamethyl-propylene amine oxime ((99m)Tc-HMPAO) single photon emission computed tomography (SPECT). Relative rCBF in areas that were found to differ significantly was also compared in groups of MA users with short-term (<6 months) and long-term (>or=6 months) abstinence. RESULTS: MA users showed decreased relative rCBF in the right anterior cingulate cortex (Brodmann area 32) relative to healthy comparison subjects. Long-term abstinent MA users had significantly greater rCBF than short-term abstinent MA users. CONCLUSIONS: We report that abstinent MA users have decreased rCBF in the anterior cingulate cortex with smaller relative decreases in subjects with prolonged abstinence.en
dc.language.isoen-
dc.publisherElsevieren
dc.subjectAdulten
dc.subjectAlcohol Drinking/physiopathologyen
dc.subjectCerebrovascular Circulation/*physiologyen
dc.subjectFemaleen
dc.subjectFunctional Lateralityen
dc.subjectGyrus Cinguli/*blood supplyen
dc.subjectHumansen
dc.subjectMaleen
dc.subject*Methamphetamineen
dc.subjectReference Valuesen
dc.subjectSubstance-Related Disorders/*physiopathology/radionuclideen
dc.subjectimaging/rehabilitationen
dc.subjectTomography, Emission-Computed, Single-Photonen
dc.titleDecreased cerebral blood flow of the right anterior cingulate cortex in long-term and short-term abstinent methamphetamine usersen
dc.typeArticleen
dc.contributor.AlternativeAuthor황재욱-
dc.contributor.AlternativeAuthor류인균-
dc.contributor.AlternativeAuthor김석주-
dc.contributor.AlternativeAuthor성영훈-
dc.contributor.AlternativeAuthor배수정-
dc.contributor.AlternativeAuthor조성남-
dc.contributor.AlternativeAuthor이호영-
dc.contributor.AlternativeAuthor이동수-
dc.identifier.doi10.1016/j.drugalcdep.2005.09.011-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Nuclear Medicine (핵의학전공)Journal Papers (저널논문_핵의학전공)
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