S-Space College of Medicine/School of Medicine (의과대학/대학원) Preventive Medicine (예방의학전공) Journal Papers (저널논문_예방의학전공)
Genetic diversity of Legionella pneumophila inferred from rpoB and dotA sequences
- Ko, K. S.; Miyamoto, H.; Lee, H. K.; Park, M. Y.; Fukuda, K.; Park, B. J.; Kook, Y. H.
- Issue Date
- Clin Microbiol Infect. 2006 Mar;12(3):254-61.
- Bacterial Proteins/*genetics; Carrier Proteins/*genetics; DNA-Directed RNA Polymerases/*genetics; *Genes, Bacterial; Genetic Variation; Japan; Korea; Legionella pneumophila/classification/*genetics; Membrane Proteins/*genetics; Molecular Sequence Data; Species Specificity
- This study characterised the population structure of Legionella pneumophila by comparing the rpoB (300-bp) and dotA (360-bp) sequences of 267 isolates (18 reference strains, 149 Korean isolates and 100 Japanese isolates). In addition to the six clonal subgroups established previously, four subgroups, P-V to P-VIII, were identified. Subgroupings based on rpoB and dotA sequences were found to correlate with the source of the isolates, and this data may be useful for future epidemiological studies. Fourteen (five Korean and nine Japanese) isolates showed incongruent subgroupings in the rpoB and dotA trees, suggesting that genetic exchange among subgroups, and even among subspecies, may occur frequently in nature.
- 1198-743X (Print)
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