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Incidence and seroprevalence of hepatitis A virus infections among young Korean soldiers

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Authors
Kang, Cheol-In; Choi, Chang-Min; Park, Tae Sung; Lee, Dong-Jun; Oh, Myoung-don; Choe, Kang-Won
Issue Date
2007-06-29
Publisher
Korean Academy of Medical Science
Citation
J Korean Med Sci. 2007 Jun;22(3):546-8.
Keywords
AdultHepatitis A/*blood/*epidemiology/immunologyHepatitis A Antibodies/immunologyHepatitis A virus/*metabolismHumansImmunoglobulin G/bloodIncidenceKoreaMaleMilitary PersonnelSeroepidemiologic Studies
Abstract
This study was performed to determine the incidence and seroprevalence of hepatitis A virus (HAV) infections in young soldiers in the Republic of Korea Army. From January 2000 through December 2004, a total of 147 hepatitis A cases were reported to the Armed Forces Medical Command. The annual incidence rates were 7.4 per 100,000 persons in 2000, 1.6 in 2001, 4.4 in 2002, 9.8 in 2003, and 6.2 in 2004, based on the reported cases among approximately 500,000 soldiers. All patients were males with a median age of 21 yr (range, 19-27). The most common symptom was nausea (86.5%), and all patients had recovered without complications. In addition, in order to evaluate the seroprevalence of HAV infection in young adults, serum samples were obtained from randomly selected young subjects among those who had been admitted to the Armed Forces Capital Hospital from September 2005 to February 2006. A total of 200 subjects were enrolled in the study to analyze the anti-HAV immune status. The overall anti-HAV IgG seropositive rate was 2% (4/200, 95% CI, 0.60-5.21%). Given the changing epidemiology of the disease and the associated increase in morbidity, it was suggested that routine HAV vaccination for Korean military personnel might be necessary.
ISSN
1011-8934 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17596668

http://hdl.handle.net/10371/29052
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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