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Usefulness of 64-slice multidetector computed tomography as an initial diagnostic approach in patients with acute chest pain

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dc.contributor.authorChang, Sung-A-
dc.contributor.authorChoi, Sang Il-
dc.contributor.authorChoi, Eue-Keun-
dc.contributor.authorKim, Hyung-Kwan-
dc.contributor.authorJung, Jin-Wook-
dc.contributor.authorChun, Eun Ju-
dc.contributor.authorKim, Kyu-Seok-
dc.contributor.authorCho, Young-Seok-
dc.contributor.authorChung, Woo-Young-
dc.contributor.authorYoun, Tae-Jin-
dc.contributor.authorChae, In-Ho-
dc.contributor.authorChoi, Dong-Ju-
dc.contributor.authorChang, Hyuk-Jae-
dc.date.accessioned2010-01-28T08:00:15Z-
dc.date.available2010-01-28T08:00:15Z-
dc.date.issued2008-07-29-
dc.identifier.citationAm Heart J. 2008 Aug;156(2):375-83. Epub 2008 May 14.en
dc.identifier.issn1097-6744 (Electronic)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18657674-
dc.identifier.urihttp://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6W9H-4SH7F06-3-9&_cdi=6683&_user=168665&_orig=search&_coverDate=08%2F31%2F2008&_sk=998439997&view=c&wchp=dGLbVlW-zSkWb&md5=eb82b6f91336457a880b27421770f65d&ie=/sdarticle.pdf-
dc.identifier.urihttp://hdl.handle.net/10371/46293-
dc.description.abstractBACKGROUND: Recently, multidetector computed tomography (MDCT) has been proposed as an accurate diagnostic tool to evaluate for coronary artery disease. However, the role of MDCT as part of the initial diagnostic for evaluating acute chest pain is less well established. METHODS: We prospectively enrolled patients presenting with acute chest pain to the emergency department (ED) and risk stratified them based on the pretest probability for an acute coronary syndrome (ACS): (1) very low, (2) low, (3) intermediate, (4) high, and (5) very high or definite. After exclusion of very low and very high risk patients, 268 patients were randomized to either immediate 64-slice cardiac MDCT or a conventional diagnostic strategy. Number of admissions, ED and hospital length of stay (LOS), and major adverse cardiac events over 30 days of follow-up were compared between the strategies based on the pretest probability for ACS. RESULTS: The number of patients ultimately diagnosed with an ACS did not differ between the 2 strategies. Emergency department LOS and total admissions were not different between strategies. Patients in the MDCT-based strategy had a decreased hospital LOS (P = .049) and fewer admissions deemed unnecessary (P = .007). Reductions in unnecessary admissions were more prominent in intermediate-risk patients (P = .015). None of the patients discharged from the ED in the MDCT-based strategy experienced major adverse cardiac events at follow-up. CONCLUSION: Use of an MDCT-based strategy in the ED as part of the initial diagnostic approach for patients presenting with acute chest pain is safe and efficiently reduces avoidable admissions in patients with an intermediate pretest probability for ACS.en
dc.language.isoenen
dc.publisherElsevieren
dc.subjectAcute Coronary Syndrome/diagnosis/*radiographyen
dc.subjectChest Pain/*etiologyen
dc.subjectCoronary Stenosis/radiographyen
dc.subjectEmergency Service, Hospitalen
dc.subjectFemaleen
dc.subjectHospitalization/statistics & numerical dataen
dc.subjectHumansen
dc.subjectLength of Stayen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectProspective Studiesen
dc.subjectTomography, X-Ray Computed/*methodsen
dc.titleUsefulness of 64-slice multidetector computed tomography as an initial diagnostic approach in patients with acute chest painen
dc.typeArticleen
dc.contributor.AlternativeAuthor장성아-
dc.contributor.AlternativeAuthor최상일-
dc.contributor.AlternativeAuthor최유근-
dc.contributor.AlternativeAuthor김형관-
dc.contributor.AlternativeAuthor정진욱-
dc.contributor.AlternativeAuthor전은주-
dc.contributor.AlternativeAuthor김규석-
dc.contributor.AlternativeAuthor조영석-
dc.contributor.AlternativeAuthor정우영-
dc.contributor.AlternativeAuthor윤태진-
dc.contributor.AlternativeAuthor채인호-
dc.contributor.AlternativeAuthor최동주-
dc.contributor.AlternativeAuthor장혁재-
dc.identifier.doi10.1016/j.ahj.2008.03.016-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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