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Cancer patients' awareness of clinical trials, perceptions on the benefit and willingness to participate: Korean perspectives

Cited 14 time in Web of Science Cited 13 time in Scopus
Authors
Kim, J. W.; Kim, S. -J.; Chung, Y. -H.; Kwon, J. -H.; Lee, H. -J.; Chung, Y. -J.; Kim, Y. J.; Oh, Do-Youn; Lee, S. -H.; Kim, Dong-Wan; Im, Seock-Ah; Kim, Tae-You; Heo, Dae Seog; Bang, Yung-Jue
Issue Date
2008-11
Publisher
Nature Publishing Group
Citation
British Journal of Cancer, Vol.99 No.10, pp.1593-1599
Keywords
cancer patientclinical trialperceptionawarenesswillingness
Abstract
To understand patients' perceptions of clinical trials (CTs) is the principal step in the enrolment of patients to CTs. However, these perceptions in eastern countries are very rare. From 12 February 2007 to 13 April 2007, we consecutively distributed the questionnaire to 842 cancer patients who initiated a first cycle of chemotherapy regardless of each treatment step in the Seoul National University Hospital. Younger age, higher educational degree, higher economic status, and possession of private cancer insurance were related with significantly higher awareness of CTs (P=0.001, P=0.006, P=0.002, and P=0.009, respectively). However, unlike awareness, perceptions on benefits of CTs were not changed according to age, educational degree, and economic status (P=0.709, P=0.920, and P=0.847, respectively). Willingness was also not changed according to age, educational degree, economic status, and private cancer insurance (P=0.381, P=0.775, P=0.887, and P=0.392, respectively). Instead, males and heavily treated patients had more positive perceptions on benefits (P=0.002 and P=0.001, respectively) and more willingness to participate in CTs (OR=1.17, 1.14-2.75: OR=1.59, 1.01-2.51, respectively). In summary, cancer patients' awareness of CTs, perceptions on the benefit in CTs, and willingness to participate are differently influenced by diverse medical and social conditions. This information would be very helpful for investigators to properly conduct CTs in eastern cancer patients.
ISSN
0007-0920
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19002181

http://www.nature.com/bjc/journal/v99/n10/pdf/6604750a.pdf

http://hdl.handle.net/10371/46306
DOI
https://doi.org/10.1038/sj.bjc.6604750
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Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Cancer Research Institute (암연구소)Journal Papers (저널논문_암연구소)
College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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