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천혜의 항생제:항균펩티드
Natural Antibiotics: Antimicrobial Peptides

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Authors
김연숙; 김정재; 최영님
Issue Date
2003
Publisher
대한치과의사협회
Citation
대한치과의사협회지 2003;41(2):116-125
Keywords
Antimicrobial peptideDefensinHistatinOral cavityOral disease
Abstract
Antimicrobial peptides are natural antibiotics evolved by many plants, invertebrate, and vertebrate to defend against the microbial infection. Antimicrobial peptides show a broad-spectrum antimicrobial activity with little opportunity for the development of resistance since they target microbial membranes that distinguish microbes from eukaryotic cells. The oral cavity is constantly exposed to microbial challenges and antimicrobial peptides play an important role in maintaining the oral health. With the increase of resistant micro-organisms to conventional antibiotics, antimicrobial peptides are attracting interests as novel antibiotics. In this review, the characteristics of antimicrobial peptides including the classification, mechanism of action, resistance, and expression in the oral cavity have been discussed in the prospect of application to oral diseases.
ISSN
1226-9638
Language
Korean
URI
http://hdl.handle.net/10371/47302
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College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
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