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ZnO Nanorod Biosensor for Highly Sensitive Detection of Specific Protein Binding

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Authors
Kim, Jin Suk; Park, Won Il; Lee, Chul-Ho; Yi, Gyu-Chul
Issue Date
2006-10
Publisher
한국물리학회 = The Korean Physical Society
Citation
J. Korean Phys. Soc. 49, 1635 (2006)
Keywords
ZnO; Nanorod; Biosensor; Field effect transistor (FET)
Abstract
We report on the fabrication of electrical biosensors based on functionalized ZnO nanorod surfaces with biotin for highly sensitive detection of biological molecules. Due to the clean interface and easy surface modification, the ZnO nanorod sensors can easily detect streptavidin binding down to a concentration of 25 nM, which is more sensitive than previously reported one-dimensional (1D) nanostructure electrical biosensors. In addition, the unique device structure with a micrometer-scale hole at the center of the ZnO nanorod's conducting channel reduces the leakage current from the aqueous solution, hence enhancing device sensitivity. Moreover, ZnO nanorod field-effect-transistor (FET) sensors may open up opportunities to create many other oxide nanorod electrical sensors for highly sensitive and selective real-time detection of a wide variety of biomolecules.
ISSN
0374-4884
Language
English
URI
http://www.kps.or.kr
http://hdl.handle.net/10371/5426
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College of Natural Sciences (자연과학대학)Dept. of Physics and Astronomy (물리·천문학부)Physics (물리학전공)Journal Papers (저널논문_물리학전공)
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