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Detection of Human Papillomavirus(HPV) DNA in Children's Genital and Respiratory Tract Papilloma and in Birth Canals of Their Mothers

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Authors
Jung, Seung Yong; Oh, Jun Kyu; Lee, Yong Suk; Park, Kyoung Chan; Kim, Kwang Hyun
Issue Date
1993-12
Publisher
Seoul National University College of Medicine
Citation
Seoul J Med 1993;34(4):311-314
Keywords
Human PapillomavirusPolymerase chain reactionCondyloma acuminatumLaryngeal papilloma
Abstract
In order to study the epidemiologic relationship between children's
papillomaviral disease and papillomaviral infection of mothers, five anogenital warts
and seven laryngeal papilloma in children were analyzed by polymerase chain reaction
to detect HPV DNA HPV type 6 was found in 8 cases and HPV type 11 in 7 cases.
Both types were found in 3 cases. From these results, anogenital warts and laryngeal
papilloma in children are found to be pure viral diseases caused by HPV type 6 and 11.
Nine cases of DNA extracted from cervical swabs from mothers of children with
condyloma or laryngeal papilloma, were examined to identify possible latent infection
of HPV. Among 9 cases, HPV DNA was found in two cases. These results suggest that
inapparent infection of HPV type 6, 11 in the birth canal may contribute to the development
of these viral diseases in their offspring aside from sexual abuse.
ISSN
0582-6802
Language
English
URI
http://hdl.handle.net/10371/5490
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 34 No.4 (1993)
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