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Biochemical Changes of Muscle Tissues in Exercise: Effect of Training and Glutamate Infusion on Lactate Metabolism : 운동중 근육조직의 생화학적 변화 : 훈련과 glutamate투여가 lactate대사에 미치는 영향
DC Field | Value | Language |
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dc.contributor.author | Park, Sang Chul | - |
dc.contributor.author | Tchai, Bum Suck | - |
dc.contributor.author | Kim, Jun | - |
dc.contributor.author | Choe, Myung Ae | - |
dc.contributor.author | Kim, Chang Keun | - |
dc.contributor.author | Lee, Mee Sook | - |
dc.contributor.author | Lee, Kwang Ho | - |
dc.contributor.author | Koh, Chang Soon | - |
dc.date.accessioned | 2009-07-14T22:46:50Z | - |
dc.date.available | 2009-07-14T22:46:50Z | - |
dc.date.issued | 1989-09 | - |
dc.identifier.citation | Seoul J Med, Vol.30 No.3, pp. 157-162 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/5552 | - |
dc.description.abstract | In exercise physiology, it is inevitable for the skeletal muscle tissues to generate
and accumulate lactate in the tissues, because lactate is the final oxidized product of glycolysis in the relative anerobic condition. The resulting accumulated lactate is supposed to be the main cause of fatigue generation in the exercising muscle tissues. To endure severe exercise, it is known that training can modify lactate metabolism via increase of anerobic threshold. In order to prevent the accumulation of lactate and to activate its clearance in the exercising muscles, it was assumed that the muscle tissue should adapt itself through training to tolerate the high dose of lactate by induction of the related enzymes. The high dose of glutamate infusion prior to exercise would shift GPT and LDH reactions in the direction of lactate elimination. In the present experiment, we determined the changes of enzymic activities such as LDH, GPT and GGTP in muscle tissues of rats after one month swimming training and lactate clearance after strenuous exerise. We compared the glutamate effect on prolonging the survival time. From these results, it was concluded that the enzymes of lactate metabolism are induced in the muscle tissues and lactate clearance is stimulated by training. Moreover, the additional supply of glutamate may improve exercise efficiency via preventing lactate accumulation in exercising muscle tissues. | - |
dc.language.iso | en | - |
dc.publisher | Seoul National University College of Medicine | - |
dc.subject | Exercise efficiency | - |
dc.subject | Lactate accumulation | - |
dc.subject | Training | - |
dc.subject | Glutamate supply | - |
dc.title | Biochemical Changes of Muscle Tissues in Exercise: Effect of Training and Glutamate Infusion on Lactate Metabolism | - |
dc.title.alternative | 운동중 근육조직의 생화학적 변화 : 훈련과 glutamate투여가 lactate대사에 미치는 영향 | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | 박상철 | - |
dc.contributor.AlternativeAuthor | 채범석 | - |
dc.contributor.AlternativeAuthor | 김준 | - |
dc.contributor.AlternativeAuthor | 최명애 | - |
dc.contributor.AlternativeAuthor | 김창근 | - |
dc.contributor.AlternativeAuthor | 이미숙 | - |
dc.contributor.AlternativeAuthor | 이광호 | - |
dc.contributor.AlternativeAuthor | 고창순 | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 162 | - |
dc.citation.number | 3 | - |
dc.citation.pages | 157-162 | - |
dc.citation.startpage | 157 | - |
dc.citation.volume | 30 | - |
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