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Serum Lipoprotein (a) Level is Decreased In Patients with Liver Diseases

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Authors
Kim, Jin Q; Hong, Young Joon; Song, Jung Han; Park, Sung Sup; Lee, Hyo Suk; Kim, Chung Yong; Kim, Sang In
Issue Date
1993-06
Publisher
Seoul National University College of Medicine
Citation
Seoul J Med 1993;34(2):147-151
Keywords
Liporotein(a)Liver diseases
Abstract
Although the synthesis and metabolism of lipoprotein(a) [Lp(a)) are
not clearly understood, the liver is considered to be the main site of Lp(a)
synthesis. We measured the serum concentration of Lp(a) and of other lipid
parameters in 153 patients with various liver diseases(lO chronic or toxic
hepatitis, 76 liver cirrhosis and 67 primary liver cancer). The serum Lp(a) was
significantly decreased or even undetectable in liver diseases compared with the
normal control group and the decrease of Lp(a) was more remarkable than the
other lipid parameters. But there were no significant differences between the 3
groups of liver diseases. Thus we suggest the possibility of Lp(a) measurement as
a novel, sensitive parameter assessing dysfunction of the liver, regardless of
dyslipidemic condition.
ISSN
0582-6802
Language
English
URI
http://hdl.handle.net/10371/5581
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 34 No.2 (1993)
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