Browse

ReIationship of Plasma Potassium and Hydrogen Ion Concentrations in Acidosis-Induced HyperkaIemia and HyperkaIemia-Induced Acidosis

Cited 0 time in Web of Science Cited 0 time in Scopus
Authors
Kim, Kyu Hyeun; Ahn, Cheol Soo; Kim, Woo Gyeum
Issue Date
1993-06
Publisher
Seoul National University College of Medicine
Citation
Seoul J Med, Vol.34 No.2, pp. 75-81
Keywords
Metabolic acidosisHyperkalemiaBlood pHCompensatory respiratory alkalosisRabbit
Abstract
The relationship between the plasma potassium concentration and
blood pH was evaluated in acidosis-induced hyperkalemia and hyperkalemiainduced
acidosis in rabbits. In the first group of animals, metabolic acidosis was
induced by an intravenous infusion of 0.1 N hydrochloric acid, and in the second
group, hyperkalemia was induced by an intravenous infusion of 20 mM potassium
chloride solution. The third group of animals was infused with both hydrochloric
acid and potassium chloride. All three groups showed metabolic acidosis, hyperkalemia,
and compensatory respiratory alkalosis. The degree of alkalosis was
most extensive in HCl infused, and least in KCl infused animals. The simultaneous
infusion of HCl and KCl induced the most extensive change in the acid-base
status, and the hydrogen and potassium ion concentrations. However the quantitative
relationship between potassium and hydrogen ion concentrations was similar
in all three groups. It is, therefore, presumed that acidosis-induced hyperkalemia
and hyperkalemia-induced acidosis involve a common mechanism.
ISSN
0582-6802
Language
English
URI
http://hdl.handle.net/10371/5589
Files in This Item:
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 34 No.2 (1993)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse