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Angiomyolipoma of the Kidney: Its Positive Expression of Immunohistochemical Markers for Schwann Cell Differentiation
신의 혈관근지방종에 있어서의 슈반세포형 면역조직화확적 표지의 발현

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Authors
Kim, Chong Jai; Park, Seong Hoe; Chi, Je G.
Issue Date
1989-12
Publisher
Seoul National University College of Medicine
Citation
Seoul J Med 1989;30(4):223-229
Keywords
AngiomyolipomaImmunohistochemistryS-100 proteinNeuron specific enolaseDesminNeural differentiation
Abstract
Ten cases of renal angiomyolipomas were immunohistochemically analyzed
for the presence of S-100 protein, neuron specific enolase (NSE) and desmin using the
avidin-biotin complex method. The composition of histologic constituents differed in each
case. The cases with predominantly smooth muscle-like solid spindle cell proliferation
showed unexpected positive reaction to S-100 protein and NSE. Among 10 cases, five were
both S-100 protein positive and NSE positive. The reaction pattern of S-100 protein and
NSE was similar. Relatively weak or minimal positive reactions to desmin were observed in
the cases and the distribution of positive reaction was different from those of S-100 protein
and NSE. The result demonstrated immunohistochemical evidence of neural or Schwarm cell
differentiation in a significant proportion of renal angiomyolipomas, and its histogenesis was
speculated.
ISSN
0583-6802
Language
English
URI
http://hdl.handle.net/10371/5600
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 30 No.4 (1989)
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