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Cell Component of Proliferative Vitreoretinal Membranes : 초자체 망막의 증식성 막의 미세구조

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dc.contributor.authorMin, Kung Hun-
dc.contributor.authorLee, Jaeheung-
dc.contributor.authorChung, Hum-
dc.date.accessioned2009-07-17T05:05:27Z-
dc.date.available2009-07-17T05:05:27Z-
dc.date.issued1985-06-
dc.identifier.citationSeoul J Med, Vol.26 No.2, pp. 171-187-
dc.identifier.issn0582-6802-
dc.identifier.urihttps://hdl.handle.net/10371/5694-
dc.description.abstractThe ultrastructure of the proliferative vitreoretinal membranes in various eye
conditions such as peripheral uveitis, penetrating eye injury, aphakic retinal detachment, and
traction retinal detachment were studied in human, and experimental study was performed in
27 pigmented rabbits to investigate the origin of cells participating in healing process of retinal
injuries. The experimental rabbits were divided into two groups according to the degree of
retinal injury; mild injury and severe injury groups. The retinal injury was made on avascular
retina two disc diameters below the optic disc by gentle touch with a 21 gauge needle tip
inserted through pars plana of rabbit eyes. The mild injury revealed a faint scratch line on the
retinal surface. The severe injury was made in the same way but retinal scratch was so deep
that choroidal damage and visible retinal hemorrhage were complicated.
The following conclusions were obtained.
1. The proliferative vitreoretinal membranes of various eye conditions were composed mainly
of fibrocyte-like cells and glial cells, and the retinal pigment epithelial cells were not found
in the membranes formed without retinal break.
2. In the mild injury group of experimental animal, only the glial proliferation was noted in
the case of the mechanical injury confined to the inner layer of the retina, and the retinal
pigment epithelial cells were found to proliferate and migrate into the inner layer when the
retinal damage extended to the outer retinal layer.
3. In the severe injury group, the proliferation of the choroidal fibroblast was noted.
On the basis of the above findings, it is suggested that the fibrocyte-like cells found at the
vitreoretinal membranes in eyes with nonrhegmatogenous retinal detachment or without retinal
detachment, are not derived from the retinal pigment epithelial cells.
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dc.language.isoen-
dc.publisherSeoul National University College of Medicine-
dc.subjectVitreoretinal membrane-
dc.subjectClosed vitrectomy-
dc.titleCell Component of Proliferative Vitreoretinal Membranes-
dc.title.alternative초자체 망막의 증식성 막의 미세구조-
dc.typeSNU Journal-
dc.contributor.AlternativeAuthor민경훈-
dc.contributor.AlternativeAuthor이재흥-
dc.contributor.AlternativeAuthor정흠-
dc.citation.journaltitle서울 의대 잡지-
dc.citation.journaltitle서울 의대 학술지-
dc.citation.journaltitleSeoul Journal of Medicine-
dc.citation.endpage187-
dc.citation.number2-
dc.citation.pages171-187-
dc.citation.startpage171-
dc.citation.volume26-
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