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HLA and Graves' Disease in Korean : 한국인에서 Graves병과 HLA
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Bo Youn | - |
dc.contributor.author | Rhee, Byong Doo | - |
dc.contributor.author | Lee, Dong Soo | - |
dc.contributor.author | Lee, Myong Sik | - |
dc.contributor.author | Kim, Geum Young | - |
dc.contributor.author | Lee, Hong Kyu | - |
dc.contributor.author | Koh, Chang-Soon | - |
dc.contributor.author | Min, Hun Ki | - |
dc.contributor.author | Lee, Munho | - |
dc.date.accessioned | 2009-07-17T05:09:19Z | - |
dc.date.available | 2009-07-17T05:09:19Z | - |
dc.date.issued | 1987-03 | - |
dc.identifier.citation | Seoul J Med, Vol.28 No.1, pp. 22-27 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/5696 | - |
dc.description.abstract | The HLA-A, -B, -C and -DR antigen distribution in 137 and 128 Korean
patients with Graves' disease, respectively, was compared with that in 220 controls. The frequency of HLA-B13, HLA-DR5 and HLA-DRw8 was significatly increased in patients with Graves' disease. The relative risk for Graves' disease in the individuals with these HLA antigens was calculated as 3,8, 4.4 and 2.3, respectively. Thus, genes promoting the development of Graves' disease in Korean are positively associated with the B13, DR5 and DRw8 haplotypes. However there was no significant correlation between the presence of these HLA antigens and the clinical features such as age at onset, sex, weight of goiter, exophthalmos, titer of autoantibodies, initial TBII values, and relapse and remission rates. Consequently, factors influencing the clinical features and the course of Graves' disease do not have a strong association with these HLA antigens. | - |
dc.language.iso | en | - |
dc.publisher | Seoul National University College of Medicine | - |
dc.subject | HLA | - |
dc.subject | Graves' disease | - |
dc.title | HLA and Graves' Disease in Korean | - |
dc.title.alternative | 한국인에서 Graves병과 HLA | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | 조보연 | - |
dc.contributor.AlternativeAuthor | 이병두 | - |
dc.contributor.AlternativeAuthor | 이동수 | - |
dc.contributor.AlternativeAuthor | 이명식 | - |
dc.contributor.AlternativeAuthor | 김금룡 | - |
dc.contributor.AlternativeAuthor | 이홍규 | - |
dc.contributor.AlternativeAuthor | 고창순 | - |
dc.contributor.AlternativeAuthor | 민헌기 | - |
dc.contributor.AlternativeAuthor | 이문호 | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 27 | - |
dc.citation.number | 1 | - |
dc.citation.pages | 22-27 | - |
dc.citation.startpage | 22 | - |
dc.citation.volume | 28 | - |
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