The Action of Panax Ginseng on the Glucose Oxidation of the Rat Liver in vitro

Abstract

1. Various concentrations of Ginseng extract increases the oxidation of glucose-l-Ctt, -and glucose-6-C14 in rat liver slices. Such effects are more prominent in Krebs-Ringer bicarbonate buffer than in Krebs-Ringer phosphate buffer, 2. Carbon dioxide production from glucose-I-Cw is much more pronounced than that from glucose -6-04• 3. Production of carbon dioxide is decreased in the hypothyroid status which induced treating animals with large amount of radioiodine(I1S1). 4. The effect of Ginseng on the glucose oxidation is more decreased in the liver slices obtained from animals of hypothyroid status than that from the normal animals. Acknowledgement: The author wishes to express his appreciation to Professor Jin Sup Oh for his kind directions in this study and also Dr. Munho Lee for his valuable advices in earring out this experiment.