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Effect of chitin/silk fibroin nanofibrous bicomponent structures on interaction with human epidermal keratinocytes

Cited 53 time in Web of Science Cited 67 time in Scopus
Authors
Yoo, Choung Ryong; Yeo, In-Sung; Park, Ko Eun; Park, Ji Hun; Lee, Seung Jin; Park, Won Ho; Min, Byung-Moo
Issue Date
2008-05
Publisher
Elsevier
Citation
International Journal of Biological Macromolecules, 42 (2008) ,324–334
Keywords
ElectrospinningNanofibrous scaffoldsHuman epidermal keratinocytes
Abstract
To fabricate a biomimetic nanostructured bicomponent scaffolds, two types of chitin/silk fibroin (SF) nanofibrous scaffolds (blend scaffolds and hybrid scaffolds) were prepared by electrospinning or simultaneous electrospinning of chitin/SF solutions. The chitin/SF bicomponent scaffolds were after-treated with water vapor, and their nanofibrous structures were almost maintained. From the cytocompatibility and cell behavior on the chitin/SF blend or hybrid nanofibrous scaffolds, the hybrid matrix with 25% chitin and 75% SF as well as the chitin/SF blend nanofibers could be a potential candidate for tissue engineering scaffolds.
ISSN
0141-8130
Language
English
URI
http://hdl.handle.net/10371/62174
DOI
https://doi.org/10.1016/j.ijbiomac.2007.12.004
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College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
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